Structure of PDB 1dmu Chain A Binding Site BS03

Receptor Information
>1dmu Chain A (length=299) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MYNLHREKIFMSYNQNKQYLEDNPEIQEKIELYGLNLLNEVISDNEEEIR
ADYNEANFLHPFWMNYPPLDRGKMPKGDQIPWIEVGEKAVGSKLTRLVSQ
REDITVREIGLPTGPDERYLLTSPTIYSLTNGFTDSIMMFVDIKSVGPRD
SDYDLVLSPNQVSGNGDWAQLEGGIQNNQQTIQGPRSSQIFLPTIPPLYI
LSDGTIAPVVHLFIKPIYAMRSLTKGDTGQSLYKIKLASVPNGLGLFCNP
GYAFDSAYKFLFRPGKDDRTKSLLQKRVRVDLRVLDKIGPRVMTIDMDK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1dmu Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1dmu Crystal structure of restriction endonuclease BglI bound to its interrupted DNA recognition sequence.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		S99 Q100 R101 E102 I104
Binding residue
(residue number reindexed from 1)		S99 Q100 R101 E102 I104
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) D116 D142 I143 K144
Catalytic site (residue number reindexed from 1) D116 D142 I143 K144
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:1dmu, PDBe:1dmu, PDBj:1dmu
PDBsum1dmu
PubMed9736624
UniProtO68557|T2B1_BACIU Type II restriction enzyme BglI (Gene Name=bglIR)

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