Structure of PDB 1bss Chain A Binding Site BS03

Receptor Information
>1bss Chain A (length=230) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LRSDLINALYDENQKYDVCGIISAEGKIYPLGSDTKVLSTIFELFSRPII
NKIAEKHGYIVEEPQQNHYPDFTLYKPSEPNKKIAIDIKATYTKIKFTLG
GYTSFIRNNTKNIVYPFDQYIAHWIIGYVYTRVKTYNINELNEIPKPYKG
VKVFLQDKWVIAGDLAGSGNTTNIGSIHAHYKDFVEGKGIFDSEDEFLDY
WRNYERTSQLRNDKYNNISEYRNWIYRGRK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1bss Chain A Residue 433 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1bss Metal ion-mediated substrate-assisted catalysis in type II restriction endonucleases
Resolution2.15 Å
Binding residue
(original residue number in PDB)		E45 D74
Binding residue
(residue number reindexed from 1)		E43 D71
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:1bss, PDBe:1bss, PDBj:1bss
PDBsum1bss
PubMed9811827
UniProtP04390|T2E5_ECOLX Type II restriction enzyme EcoRV (Gene Name=ecoRVR)

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