Structure of PDB 7bl5 Chain 9 Binding Site BS03

Receptor Information
>7bl5 Chain 9 (length=338) Species: 511145 (Escherichia coli str. K-12 substr. MG1655) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKFVDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVWMEAD
ENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQG
TGETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKR
ELLLELMLLADVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGV
VRMDNEKSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRVLLHLIDIDPI
DGTDPVENARIIISELEKYSQDLATKPRWLVFNKIDLLDKVEAEEKAKAI
AEALGWEDKYYLISAASGLGVKDLCWDVMTFIIENPVV
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7bl5 Chain 9 Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7bl5 Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		K172 S173
Binding residue
(residue number reindexed from 1)		K172 S173
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.-
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0017111 ribonucleoside triphosphate phosphatase activity
GO:0019003 GDP binding
GO:0019843 rRNA binding
GO:0032561 guanyl ribonucleotide binding
GO:0043023 ribosomal large subunit binding
GO:0046872 metal ion binding
GO:0097216 guanosine tetraphosphate binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0007059 chromosome segregation
GO:0022611 dormancy process
GO:0042254 ribosome biogenesis
GO:0042255 ribosome assembly
GO:0090071 negative regulation of ribosome biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7bl5, PDBe:7bl5, PDBj:7bl5
PDBsum7bl5
PubMed33639093
UniProtP42641|OBG_ECOLI GTPase ObgE/CgtA (Gene Name=obgE)

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