Structure of PDB 7zah Chain 7 Binding Site BS03

Receptor Information
>7zah Chain 7 (length=595) Species: 272844 (Pyrococcus abyssi GE5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RIRQPIIAVLGHVDHGKTTLLDRIRKTNVAAKEAGGITQHIGATEVPIEV
VKKIAGPLIKLWKAEIKLPGLLFIDTPGHEAFTSLRARGGSLADLAVLVV
DINEGFQPQTIESIEILRKYRTPFVVAANKIDRIKGWVIEEDEPFLMNIK
KQDQRAVQELETKLWELIGKFYEFGFQANRFDRVQNFTRELAIVPISAKY
GIGIAELLVLIAGLSQRYLEEKLKIEVEGPARGTILEVREEPGLGHTIDV
IIYDGTLHKDDTIVVGGKDKAIVTKIRALLKPKPLDEIRDPRFRFDYVDE
VTAAAGVKIAAPGLEEALAGSPVIAAPTPEDVEKAKQEILEQIERVVIST
DKVGVIVKADTLGSLEALSKELQEKEIPIRKADVGNVSKTDVMEALSVKE
EEPKYGVILGFNVKVNEDAEEVAKAKDVKIFVGNVIYKLIEDYEEWVKEE
EEKKKRELLSKVTFPGVIRLYPDERYVFRRSNPAIVGIEVIEGRIKPGVT
LIKQNGQKVGVIRSIKSRDEFLQEAKKGQAVAIAIEGAIVGRHIHPGETL
YVDLSRDDAITLLKHLRDTLEDTDIKALKMIAKVKAKEDPFWRAI
Ligand information
Ligand IDMET
InChIInChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChIKeyFFEARJCKVFRZRR-BYPYZUCNSA-N
SMILES
SoftwareSMILES
CACTVS 3.341CSCC[CH](N)C(O)=O
OpenEye OEToolkits 1.5.0CSCCC(C(=O)O)N
CACTVS 3.341CSCC[C@H](N)C(O)=O
OpenEye OEToolkits 1.5.0CSCC[C@@H](C(=O)O)N
ACDLabs 10.04O=C(O)C(N)CCSC
FormulaC5 H11 N O2 S
NameMETHIONINE
ChEMBLCHEMBL42336
DrugBankDB00134
ZINCZINC000001532529
PDB chain7zah Chain 4 Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7zah Role of aIF5B in archaeal translation initiation.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		Y479 F481 A533 V534
Binding residue
(residue number reindexed from 1)		Y476 F478 A530 V531
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003743 translation initiation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006413 translational initiation

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Molecular Function
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Biological Process
External links
PDB RCSB:7zah, PDBe:7zah, PDBj:7zah
PDBsum7zah
PubMed35694843
UniProtQ9UZK7|IF2P_PYRAB Probable translation initiation factor IF-2 (Gene Name=infB)

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