Structure of PDB 5mdv Chain 7 Binding Site BS03

Receptor Information

>5mdv Chain 7 (length=362) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

INPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQPDVWNEPERA
QALGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAEL
DALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYL
RWAESRGFKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVR
KSPFDSGGRRHTSFSSAFVYPEVDDDIDIEINPADLRIDVYRTSGAGGQH
VNRTESAVRITHIPTGIVTQCQNDRSQHKNKDQAMKQMKAKLYELEMQKK
NAEKQAMEDNKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQAVLDGSL
DQFIEASLKAGL

Ligand information

>5mdv Chain 5 (length=76) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gcgggguugagcagccugguagcucgucgggcucauaacccgaagaucgu
cgguucaaauccggcccccgcaacca

<<<<<<..<<<<.........>>>>.<<<<<.......>>>>>.....<<
<<<.......>>>>>>>>>>>.....

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5mdv Translational termination without a stop codon.
Resolution	2.97 Å
Binding residue (original residue number in PDB)	E172 V173 R278
Binding residue (residue number reindexed from 1)	E169 V170 R275

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003747	translation release factor activity
GO:0016149	translation release factor activity, codon specific

	Biological Process
GO:0006412	translation
GO:0006415	translational termination
GO:0075523	viral translational frameshifting

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol

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Cellular Component

External links

PDB	RCSB:5mdv, PDBe:5mdv, PDBj:5mdv
PDBsum	5mdv
PubMed	27934701
UniProt	P07012\|RF2_ECOLI Peptide chain release factor RF2 (Gene Name=prfB)

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