Structure of PDB 6lqr Chain 5I Binding Site BS03

Receptor Information
>6lqr Chain 5I (length=461) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKIKTIKRSADDYVPVKSTQESQMPRNLNPELHPFERAREYTKALNATKL
ERMFAKPFVGQLGYGHRDGVYAIAKNYGSLNKLATGSADGVIKYWNMSTR
EEFVSFKAHYGLVTGLCVTQPRFHDKKPDLKSQNFMLSCSDDKTVKLWSI
NVDDYSNKNNEEGLIRTFDGESAFQGIDSHRENSTFATGGAKIHLWDVNR
LKPVSDLSWGADNITSLKFNQNETDILASTGSDNSIVLYDLRTNSPTQKI
VQTMRTNAICWNPMEAFNFVTANEDHNAYYYDMRNLSRSLNVFKDHVSAV
MDVDFSPTGDEIVTGSYDKSIRIYKTNHGHSREIYHTKRMQHVFQVKYSM
DSKYIISGSDDGNVRLWRSKAWERSNVKTTREKNKLEYDEKLKERFRHMP
EIKRISRHRHVPQVIKKAQEIKNIELSSIKRREANERRTRKDMPYISERK
KQIVGTVHKYE
Ligand information
>6lqr Chain SA (length=1283) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aagauaguuaucugguugauccugccaguagucauaugcuugucucagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaaggcucau
uaaaucaguuaucguuuauuugauaguuccaugguauaacugugguaauu
cuagagcuaauacaugcuaaucucgacccuuuggaagagauguauuuauu
agaucaaugucuucggacucuuugaugaaauaacuuuucgaaucgcaugg
ccuugugcuggcgaugguucauucaaauuucugcccuaucaacuuucgau
gguaggauaguggccuaccaugguuucaacggguaacggggaauaagggu
ucgauuccggagagggagccugagaaacggcuaccacauccaaggaaggc
agcaggccaaauuacccaauccuaauucagggagguagugacaauaaaua
acgauacagggcccauucgggucuuguaauuggaaugaguacaauguaaa
uaccuuaacgaggaacaauuggagggcaagucuggugccagcagccgcgg
uaauuccagcuccaauagcguauauuaaaguuguugcagaagcucguagu
ugaacuggcccgguuggccgguccggauuuccaacggggccuugguucua
uuuucuaggacugauuaauagggacggucgggggcaucaguauucaauug
ucagaggugaaauucuuggauuuauugaagacuaacuacugcgaaagcau
uugccaaggacguuuucauuaaucaagaacgccgacuagggaucgggugg
uguuuuuuuaaugacccacucggcaccuuacgagacuggggggaguaugg
ucgcaaggcugaaacuuaaaggaauugacggaagggcaccaccaggagug
gagccugcggcucaacacggggaaacucaccagguccagacacaauaagg
auugacauucuugauuuugugggugguggugcauugaugcccuuguucug
ggccacgcgcgcuacacugacggagccagcgagucuagugaaacuccguc
gugcuggcaacgaggaauuccuaguaagcgcaagucaucagcuugcguug
auuacgucccugcccuuuguacacaccgcccgucgcuaguaccgauugaa
uggcuuagugaggccucaggaucugcuuagagaagggggcaacuccaucu
cagagcggagaauuuggacaaacuuggucauuuagaggaacuaaaagugg
uuuccguaggugaaccugcggaaggaucauuaa
............................<<<<.<<<<<<........<<<
.<<...<<....<<....<<..........>>...>>.>>.....<<<..
.....<<<..<<..<<....<<<..........<.....<<.<<......
.>>.>>......>.......<<<<............>>>>.....<<<<<
...<<<<..............>>>>...>>>>>.........<<<<...<
<.....>>..>>>>....>>>...>>>>..>>>.<<<....<<<....<<
<<<<<<.......>>>>>>>>>>>......>>>.....<<..........
.....>>..>>>.<<.<<<..........>>>.>>.<.<<....>>.>..
..>>>>>......<<<....<<<.....>>>..>>>..............
.<<<<<<<.<<<<<....>>>>>.>>>.>>>>......<<..<.......
....>..>>.........<<<<<<.......<<<....>>>.........
.........>>>>>>..>>>>>>>>>>.........<....<.<<...<<
<.<<..<<<<<.<<<<<..<.......>..>>>>>.>>>>>.<..<<..<
...>..>>.>....>>....<<<<<<.<<...<<<<..<<..<<<<<<.<
...<<<......>>>......>.>>>>>>..>>.......<<....>>..
.>>>>...>>>>>.>>>...>>>...>>.>..<<...<<<..<<<<<<<<
.<<<........>>>>>>>>>>>..>>>..>>.....>............
........<<.........>>.....<<<<<<<<<<<<..<<.<<<<<<.
.<<<.<<<<.......................<<.<....<<<<<.....
...<.....>......>>>>>......<<<........>>>...>.>>..
.....>>>>.>>>.....<<<<<<<..................>>>>>>>
................>>>>>>....<<<<<<<<.......>>>>>>>>.
.....>>...>>>>>>>............>>>>>..<<<<.<<.....<<
<<<<<.<<<..<.<<......<<<<<<<...<<.<<<......>>>.>>.
..>>>>>>>......>>.>..>>>.>>>>>>>....>>.>>>>.......
.<<<<<<<<<....>>>>>>>>>..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6lqr Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
Resolution8.6 Å
Binding residue
(original residue number in PDB)		F275 D290 R292 R296 N299 V300 K302 H336 G337 H338 R412 R415 H416 V419 K424 K425 N431 E433 S436 K438 R439 R440 N443 E444 K449 Y453 E456 R457
Binding residue
(residue number reindexed from 1)		F267 D282 R284 R288 N291 V292 K294 H328 G329 H330 R404 R407 H408 V411 K416 K417 N423 E425 S428 K430 R431 R432 N435 E436 K441 Y445 E448 R449
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6lqr, PDBe:6lqr, PDBj:6lqr
PDBsum6lqr
PubMed32943522
UniProtP33750|DCA13_YEAST Protein SOF1 (Gene Name=SOF1)

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