Structure of PDB 6xhw Chain 2l Binding Site BS03

Receptor Information

>6xhw Chain 2l (length=122) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRK
VAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGV
YDAAGVKDRKKSRSKYGTKKPK

Ligand information

InChI=1S/Mg/q+2

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Mg

Name

MAGNESIUM ION

PDB chain

6xhw Chain 2a Residue 3142 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	6xhw Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance.
Resolution	2.5 Å
Binding residue (original residue number in PDB)	R97 Y98
Binding residue (residue number reindexed from 1)	R93 Y94
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6xhw, PDBe:6xhw, PDBj:6xhw
PDBsum	6xhw
PubMed	33462493
UniProt	Q5SHN3\|RS12_THET8 Small ribosomal subunit protein uS12 (Gene Name=rpsL)

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