Structure of PDB 8ud7 Chain 2Q Binding Site BS03

Receptor Information
>8ud7 Chain 2Q (length=141) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAA
RVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPG
RVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ
Ligand information
>8ud7 Chain 2w (length=69) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cccggauagcucagggagagcaggggauugaaaauccccguguccuuggu
ucgauuccgaguccgggca
<<<<<<..<<<<.....>>>>.<<<<<<.....>>>>>>.....<<<<<.
......>>>>>>>>>>>..
Receptor-Ligand Complex Structure
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PDB8ud7 An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance
Resolution2.55 Å
Binding residue
(original residue number in PDB)
R51 R60
Binding residue
(residue number reindexed from 1)
R51 R60
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8ud7, PDBe:8ud7, PDBj:8ud7
PDBsum8ud7
PubMed38359125
UniProtP60489|RL16_THET8 Large ribosomal subunit protein uL16 (Gene Name=rplP)

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