Structure of PDB 8vtu Chain 20 Binding Site BS03
Receptor Information
>8vtu Chain 20 (length=83) Species:
300852
(Thermus thermophilus HB8) [
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AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNV
GMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPL
Ligand information
>8vtu Chain 2x (length=77) [
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cgcgggguggagcagccugguagcucgucgggcucauaacccgaaggucg
ucgguucaaauccggcccccgcaacca
.<<<<<<..<<<<.........>>>>.<<<<<.......>>>>>.....<
<<<<.......>>>>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB
8vtu
Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
A2 G6 L7 R11
Binding residue
(residue number reindexed from 1)
A1 G5 L6 R10
External links
PDB
RCSB:8vtu
,
PDBe:8vtu
,
PDBj:8vtu
PDBsum
8vtu
PubMed
39039256
UniProt
P60493
|RL27_THET8 Large ribosomal subunit protein bL27 (Gene Name=rpmA)
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