Structure of PDB 8twb Chain 2 Binding Site BS03

Receptor Information
>8twb Chain 2 (length=340) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKLAAEQSLAQQPWVEKYRPKNLDEVTAQDHAVTVLKKTLKSANLPHMLF
YGPPGTGKTSTILALTKELYGPDLMKSRILELNASDERGISIVREKVKNF
ARLTVSKPSKHDLENYPCPPYKIIILDEADSMTADAQSALRRTMETYSGV
TRFCLICNYVTRIIDPLASRCSKFRFKALDASNAIDRLRFISEQENVKCD
DGVLERILDISAGDLRRGITLLQSASKGAQYLGDGKNITSTQVEELAGVV
PHDILIEIVEKVKSGDFDEIKKYVNTFMKSGWSAASVVNQLHEYYITNDN
FDTNFKNQISWLLFTTDSRLNNGTNEHIQLLNLLVKISQL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8twb Chain 2 Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8twb Cryo-EM reveals that Ctf18-RFC collaborates with PolE to load the PCNA clamp onto a leading strand DNA
Resolution3.2 Å
Binding residue
(original residue number in PDB)
T72 D140
Binding residue
(residue number reindexed from 1)
T59 D127
Annotation score4
External links
PDB RCSB:8twb, PDBe:8twb, PDBj:8twb
PDBsum8twb
PubMed
UniProtP40348|RFC2_YEAST Replication factor C subunit 2 (Gene Name=RFC2)

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