Structure of PDB 8vtu Chain 1G Binding Site BS03
Receptor Information
>8vtu Chain 1G (length=181) Species:
300852
(Thermus thermophilus HB8) [
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PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDAR
ILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWI
FLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDA
LRGMDIAVVTTAETDEEARALLELLGFPFRK
Ligand information
>8vtu Chain 1x (length=77) [
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cgcgggguggagcagccugguagcucgucgggcucauaacccgaaggucg
ucgguucaaauccggcccccgcaacca
.<<<<<<..<<<<.........>>>>.<<<<<.......>>>>>.....<
<<<<.......>>>>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB
8vtu
Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
S76 S78
Binding residue
(residue number reindexed from 1)
S75 S77
External links
PDB
RCSB:8vtu
,
PDBe:8vtu
,
PDBj:8vtu
PDBsum
8vtu
PubMed
39039256
UniProt
Q5SHQ0
|RL5_THET8 Large ribosomal subunit protein uL5 (Gene Name=rplE)
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