Structure of PDB 7nhn Chain 0 Binding Site BS03

Receptor Information
>7nhn Chain 0 (length=461) Species: 169963 (Listeria monocytogenes EGD-e) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TIEINQLKIEVADRVLVEIPHLLVSKKARIGIIGQNGLGKTTLMEVIAGA
KEATSGTVTTQGKLAYIKQLSTDTSTKSGGEKTRKATQHAMRQNPSVLLA
DQPTSNLDVESVKHLERQWSDFHGALIIISHDRAFLDALCTEIWEIKNQK
IHVYKGNYHAYLEQKQQQENQAELAYKEFKNKKKQLQASQTHHEIEAGRI
VKPGKRLNNKEASAFKAGKGTQQKKQHSTIKALEKRIERLGNVEKPHTTK
PIKIITPDNRVIKKGNTILSAKETAYEIAGRKLFETKAFSIKAGDKVALI
GENASGKTTFLKEIIQENPNLLCNPQAKIAYFDQELNGLNQTKSLLENIS
EISVQTKQVNREVLGSMHFKESDLHKEVRMLSGGERVKLLLSMLLLSDAN
FLILDQPTNYLDIYAMEALETLIKQFAGTVLFVSHDRTFVNHVAEQLLVI
ENNEMNFHRMT
Ligand information
>7nhn Chain a (length=1513) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gagaguuugauccuggcucaggacgaacgcuggcggcgugccuaauacau
gcaagucgaacgaacggauguuaguggcggacgggugaguaacacguggg
caaccugccuguaaguuggggauaacuccgggaaaccggggcuaauaccg
aaugauaaaguguggcgcaugccacgcuuuugaaagaugguuucggcuau
cgcuuacagaugggcccgcggugcauuagcuaguugguaggguaauggcc
uaccaaggcaacgaugcauagccgaccugagagggugaucggccacacug
ggacugagacacggcccagacuccuacgggaggcagcaguagggaaucuu
ccgcaauggacgaaagucugacggagcaacgccgcguguaugaagaaggu
uuucggaucguaaaguacuguuguuagagaagaacaaggauaagaguaac
ugcuugucccuugacgguaucuaaccagaaagccacggcuaacuacgugc
cagcagccgcgguaauacguagguggcaagcguuguccggauuuauuggg
cguaaagcgcgcgcaggcggucuuuuaagucugaugugaaagcccccggc
uuaaccggggagggucauuggaaacuggaagacuggagugcagaagagga
gaguggaauuccacguguagcggugaaaugcguagauauguggaggaaca
ccaguggcgaaggcgacucucuggucuguaacugacgcugaggcgcgaaa
gcguggggagcaaacaggauuagauacccugguaguccacgccguaaacg
augagugcuaaguguuaggggguuuccgccccuuagugcugcagcuaacg
cauuaagcacuccgccuggggaguacgaccgcaagguugaaacucaaagg
aauugacgggggcccgcacaagcgguggagcaugugguuuaauucgaagc
aacgcgaagaaccuuaccaggucuugacauccuuugaccacucuggagac
agagcuuucccgggacaaagugacagguggugcaugguugucgucagcuc
gugucgugagauguuggguuaagucccgcaacgagcgcaacccuugauuu
uaguugccagcauuuaguugggcacucuaaagugacugccggugcaagcc
ggaggaagguggggaugacgucaaaucaucaugccccuuaugaccugggc
uacacacgugcuacaauggauaguacaaagggucgcgaagccgcgaggug
gagcuaaucccauaaaacuauucucaguucggauuguaggcugcaacucg
ccuacaugaagccggaaucgcuaguaaucguggaucagcaugccacggug
aauacguucccgggccuuguacacaccgcccgucacaccacgagaguuug
uaacacccgaagucgguaggguaaccggagccagccgccgaaggugggac
agauaauuggggugaagucguaacaagguagccguaucggaaggugcggc
uggaucaccuccu
..<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<.<
<<..<<<..<<.<<<<..>>>>.>>>>>......<<........<<<<<<
<..<<...<<<<<<<<<.<<.....<<<<<<....>>>>>>......>>.
>.....<<<<<<<<<<....>>>>>>>>>>.....<<<<<<....>>>>>
>>>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<<.......>>
>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<
<<.<.........>>>>>>.<<<<....>>>>...>>>>>>.........
<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<
<....>>>>.....>>>>...<<<<<<<.......<<<<<<<<<......
..>>>>>>>.>>.......>>>>>>...>..<<<<<(((...<<<<<...
..<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<
<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<.......<<<<<<.
....>>>>>>.....>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<
<<<<....<<<<<<<<<..<<<......>>>.....>>>>>>>>>.....
......<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....
<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>........
..<<<<<<..<<<<<<<<<<<<<....>>>>>>>>>>>>>...<<..))>
>.....>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))
).]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<....
....>>..........<<<<<<<......<<<<<<<....<<<<<....>
>>>>....<<<>>>.>>>>>.>>.<<<.<<<..<<<<<<.......<<<<
<<<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<
<<<..<<<..<<......>>>>>...>>>>>>>.....<<<<<....>>>
>>........>>>>.........>>>...>>>>>>>>>...>>>>>>>..
.>>.>>>>>>>>.....<<<<<<<.....<<<..<<...<<<....>>>.
..>>....>>>.....>>>>>>>......<....<<<<<<<........>
>>>>>>....>.....>>>>>>....<<<<<<<.........>>>>>>>.
.....>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<
<..<<<<....<.<<<<..<<<..<<>>.>>>.>>>>.>...>>>>..>>
>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>
>............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7nhn Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		K265 N268 T269
Binding residue
(residue number reindexed from 1)		K263 N266 T267
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:7nhn, PDBe:7nhn, PDBj:7nhn
PDBsum7nhn
PubMed34117249
UniProtQ8Y8I3

[Back to BioLiP]