Structure of PDB 6zxf Chain y Binding Site BS02

Receptor Information
>6zxf Chain y (length=233) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVEHVVANAGAFLRHAALQDIGKNIYTIREVVTEIRDKATRRRLAVLPYE
LRFKEPLPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSH
LKQEPQKVRVGCLTTDFAMQNVLLQMGLHVLAVNGMLIREARSYILRCHG
CFKTTSDMSRVFCSHCGNKTLKKVSVTVSTLHMHFSRNPKVLNPRGLRYS
LPTPKGGKYAINPHLTEDQRFPQLRLSQKPDYI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6zxf Chain y Residue 500 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6zxf Structural basis for the final steps of human 40S ribosome maturation.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		C270 C273 C285 C288
Binding residue
(residue number reindexed from 1)		C148 C151 C163 C166
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0004521 RNA endonuclease activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006364 rRNA processing
GO:0007601 visual perception
GO:0030490 maturation of SSU-rRNA
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0030688 preribosome, small subunit precursor

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zxf, PDBe:6zxf, PDBj:6zxf
PDBsum6zxf
PubMed33208940
UniProtQ9ULX3|NOB1_HUMAN RNA-binding protein NOB1 (Gene Name=NOB1)

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