Structure of PDB 3j46 Chain y Binding Site BS02

Receptor Information
>3j46 Chain y (length=435) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGIDAAVLAKLLEQ
QRGTIIEMFNMFCGGALSRASIFALGIMPYISASIIIQLLTVVHPTLAEI
KKEGESGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFA
FYFTAVVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAH
TIEQARQGDLHFLVLLLVAVLVFAVTFFVVFVERGQRRIVVNYAKRQQGR
RVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGWNWLTT
ISLYLQPGQPLYVLLYASAIIFFCFFYTALVFNPRETADNLKKSGAFVPG
IRPGEQTAKYIDKVMTRLTLVGALYITFICLIPEFMRDAMKVPFYFGGTS
LLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKG
Ligand information
>3j46 Chain 2 (length=36) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaggguuccuguccaacguuaaucggggcaggguga
.......<<<<<<...<<.....>>.>>>>>>....
Receptor-Ligand Complex Structure
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PDB3j46 Structure of the SecY channel during initiation of protein translocation.
Resolution10.1 Å
Binding residue
(original residue number in PDB)
A249 K250 R251 Q252 G355 R357
Binding residue
(residue number reindexed from 1)
A244 K245 R246 Q247 G350 R352
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005048 signal sequence binding
GO:0005515 protein binding
GO:0008320 protein transmembrane transporter activity
Biological Process
GO:0006605 protein targeting
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation
GO:0006886 intracellular protein transport
GO:0015031 protein transport
GO:0032978 protein insertion into membrane from inner side
GO:0043952 protein transport by the Sec complex
GO:0065002 intracellular protein transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0031522 cell envelope Sec protein transport complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3j46, PDBe:3j46, PDBj:3j46
PDBsum3j46
PubMed24153188
UniProtP0AGA2|SECY_ECOLI Protein translocase subunit SecY (Gene Name=secY)

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