Structure of PDB 7q0f Chain x Binding Site BS02

Receptor Information

>7q0f Chain x (length=172) Species: 237561 (Candida albicans SC5314)

VRYAATPANPAKSASARGSYLRVSFKNTRETAQAINGWKLEKAQKYLDQV
LDHQRAIPFRRYNSSIGRTGQGKEFGVTKARWPAKSVNFVKDLLRNAQAN
AEAKGLDSSKLVISHIQVNHAPKQRRRTYRAHGRINAYQSTPSHIELTLT
EEQIRLNSRQRGRLASQKRLTA

Ligand information

>7q0f Chain 4 (length=158)

aaacuuucaacaacggaucucuugguucucgcaucgaugaagaacgcagc
gaaaugcgauacguaauaugaauugcagauauucgugaaucaucgaaucu
uugaacgcacauugcgcccucugguauuccggagggcaugccuguuugag
cgucguuu

.........................................<<<<<<.((
.....>>>.....<.<<<<.....))............>>.>>..>...>
>>....<<.....>><<<<<<<<<....>>>>>>>>>.............
........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7q0f E-site drug specificity of the human pathogen Candida albicans ribosome.
• Resolution: 2.64 Å
• Binding residue (original residue number in PDB): R3 A5 R61 R62 N120 H121 P123 H145
• Binding residue (residue number reindexed from 1): R2 A4 R60 R61 N119 H120 P122 H144

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0009986 cell surface
• GO:0015934 large ribosomal subunit
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7q0f, PDBe:7q0f, PDBj:7q0f
• PDBsum: 7q0f
• PubMed: 35613268
• UniProt: Q59TE0|RL17B_CANAL Large ribosomal subunit protein uL22 (Gene Name=RPL17B)