Structure of PDB 5apn Chain x Binding Site BS02

Receptor Information
>5apn Chain x (length=579) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALAISHEDTQILLKDKNILQESVLNKYRTAGQIAQTALKYVTSLINDSYH
SKTTQRQLTVPELCLLTDSFILTRLEQYYKNKVNERGIAIPTTIDIDQIS
GGWCPEIDDTQNLLNWNKGKDSTFASSVTGTLRPGDLVKITLGVHIDGYT
SEVSHTMVIYPVDETKPILQPTGPLLGGKADAVAAAHIAMETVVALLACA
LTPEKLPASLGGTSSGITGQLIRTIVDTIARSYNCGVVPGSRVRRIRRFL
AGQNEGIVAEREYKGVVWTESHQEADLLSNTDAKDLTVVDRGQSTPFTNV
SAIPSDDFVVQSGEVYLIDLKMASLEHCTKKGLVTLETVDSYTGKSHKAG
ELIARPGAYVRDFAQTHILKLKTSRQLLTKIDKQGVYPFKLSHLSSNFPF
VHENEEELQSLKKDLKSFRLGMSEISNNYLCVESPIQIARWVPWDHILKA
TNPNGNLSYDATSTLTLPGHELPLPKLGVSAIKLKSLMNSTKESISLPVA
RECNTIVLCDSSVSTTDRPELLRLTGGSKTCQPSWIHSQHELNPQDSIVQ
GIFQLATLAKDKRFGLLLKETQPMKQKSV
Ligand information
>5apn Chain 8 (length=158) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaacuuucaacaacggaucucuugguucucgcaucgaugaagaacgcagc
gaaaugcgauacguaaugugaauugcagaauuccgugaaucaucgaaucu
uugaacgcacauugcgccccuugguauuccagggggcaugccuguuugag
cgucauuu
.........................................<<<<<<.<<
.....>>>.....(.<<<......>>..............>>>..)...>
>>....<<.....>><<<<<<<<<....>>>>>>>>>.............
........
Receptor-Ligand Complex Structure
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PDB5apn Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation.
Resolution3.91 Å
Binding residue
(original residue number in PDB)		K346 H348 K493
Binding residue
(residue number reindexed from 1)		K345 H347 K492
Enzymatic activity
Enzyme Commision number 3.-.-.-
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0000055 ribosomal large subunit export from nucleus
GO:0006508 proteolysis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0030687 preribosome, large subunit precursor

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5apn, PDBe:5apn, PDBj:5apn
PDBsum5apn
PubMed26709046
UniProtQ03862|ARX1_YEAST Probable metalloprotease ARX1 (Gene Name=ARX1)

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