Structure of PDB 5t2a Chain w Binding Site BS02

Receptor Information
>5t2a Chain w (length=187) Species: 5661 (Leishmania donovani) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VKVKSLCTLQIPEGVTVDVKGRKVTVTGKRGTLTKDLTHLQLDLRVDKKN
RTFTVIRWFGSKIPIACLNTTKAHVQNMITGVTKGYRFKVRCAYAHFPIN
VSVDGQNIEVRNFLGEKRVRRQLVPSSVKVSQTDPSKVKDEIIFDGNDLE
QVSREAAVLHQMCLVKKKDIRKFLDGIYVQTKTNIEG
Ligand information
>5t2a Chain B (length=1064) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cccaacugcagaccguacucaucaccgcaucagguccccaagcauagaau
gcucugguacauagagaaagguacacucagggaagucggcaaaauagaug
cguaaguucgcaagaagcauuggcucugagggcaauugccaacucagaac
ugcuuacggcggggaauccaacuguauaauuaaaacauagguuugugaug
cauccaagugguguauaucgcaaacugauuucugcccagugcucugaaug
ucaacgugacgagauucaccgacgcgcggguaaacggcgggaguaacuau
gacucucuuaagguagccaaaugccucgucuuccaauuagagacgcgcau
gaauggauuaaugagauucccucugucccgaguuacuaucuagcgaaacg
acagucaagggaacggacuugaagggcuaagcggggaaagaagacccugu
ugaguuugacuccagucuggcucugugcggcgacguugcuucacuuaucg
aaugaagagaccaaugggcgugcuguaaacugaaccaacggguccggagu
cuuguuucgagacaucugccagauggggaguuuggcuggggcggcauauc
uguuacacgacaacgcagguguccuaaggcgagcucagugggaacagaaa
ucucacguagaacacaagcguaaaagcuugcuugauuaacgauuuccagu
acgaaucgagacugcgaaagcaaggccagcgauccuuugcgaagaauagg
aaauaugaacaaaucauaccagaggugucagaauaauuaccacagggaua
acuggcuuguggcggccaagcguucauagcgacgucgcuuuuugauccuu
cgaugucggcucuuccuaaccuagcgccgcagaagacgcuaaggguugga
uuguucacccacugacagggaacgugagcuggguuuagaccgucgugaga
cagguugguuuuacccuacuuagcuggaaauugcgagaaaagauuauccg
cgcaaagcggaggcaguccgucugggucugccguucgguggcaugugcuu
ggcgcugccaucuc
........................<<......>>......<<<<.....>
>>>........<<<<....<<<<.<<<<.<<.........<.....<<<<
<...............>>>>><<.<<<<<<<<<<..>>>>..>>>>>>.>
>..........<<<<<<<<<..<<<.........>>>..<<<<<<<....
<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<.....<
<....<<<<......>>>>....>>..>>>>..>>>>><<<<<<......
.>>>>>>........<...........<<<<<.......>>>>>.....>
.....>>....>>.>>>>>>>..>..>>.>>>>>>>>.>>>>........
....<<<<<........>>>>>..<<<<<<<..<<<.<<......<<<<.
<<<<<<..<<<<<.<<<<<<<...<<<.<<<<<..>>>>>.>>>...<<<
<<.....<<<<...........................<<<..>>>..>>
>>...>>>>>.......>>>>>>>..>>>>>...<<<.....>>>..<<<
<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.......
>>>>>>.....<<......>>....>>>>>>>...<<...<<<<<.....
..>>>>>..>>.<<<....>>>.>>........<<<<<<...........
...<<<<.......>>>>.>>>>>>.........>>>>..>>>>>>....
...<<.<.<.<<<<<<...<<.......>>...>>>>>>...>>.>.>..
.....<<<<<.<<<<<<..<<<<<<<.<......>.>>>>..>>>.<<<.
........>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>
>.>>>>....>>..>>>.>>>>>>>......................<<<
<.....>>>>.<<<<<<<<....>>>.>>>>>....<<<<<<<..<....
...>.>>>>>>>..
Receptor-Ligand Complex Structure
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PDB5t2a Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		K167 K169 D170 R172 F174
Binding residue
(residue number reindexed from 1)		K166 K168 D169 R171 F173
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5t2a, PDBe:5t2a, PDBj:5t2a
PDBsum5t2a
PubMed27752045
UniProtA0A3S7WWL2

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