Structure of PDB 8pva Chain v Binding Site BS02

Receptor Information

>8pva Chain v (length=78) Species: 562 (Escherichia coli)

GSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRDH
TLFAKADGKVKFEVKGPKNRKFISIEAE

Ligand information

>8pva Chain b (length=119)

ugccuggcggccguagcgcgguggucccaccugaccccaugccgaacuca
gaagugaaacgccguagcgccgaugguaguguggggucuccccaugcgag
aguagggaacugccaggca

<<<<<<<<<<.....<<<<<<<<....<<<<<<<.............>>>
>..>>>...>>>>>>.>>.<<.......<<<<<<<<...>>>>>>>>...
....>>...>>>>>>>>>>

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8pva Structure determination by cryoEM at 100 keV
• Resolution: 4.5 Å
• Binding residue (original residue number in PDB): G73 P74 N76
• Binding residue (residue number reindexed from 1): G66 P67 N69

Gene Ontology

Molecular Function

• GO:0000049 tRNA binding
• GO:0003735 structural constituent of ribosome
• GO:0005515 protein binding
• GO:0019843 rRNA binding
• GO:0043022 ribosome binding

Biological Process

• GO:0000027 ribosomal large subunit assembly
• GO:0001558 regulation of cell growth
• GO:0002181 cytoplasmic translation
• GO:0006412 translation
• GO:0042256 cytosolic ribosome assembly
• GO:0090070 positive regulation of ribosome biogenesis
• GO:1902626 assembly of large subunit precursor of preribosome

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8pva, PDBe:8pva, PDBj:8pva
• PDBsum: 8pva
• PubMed: 38011573
• UniProt: P0A7L8|RL27_ECOLI Large ribosomal subunit protein bL27 (Gene Name=rpmA)