Structure of PDB 8ine Chain v Binding Site BS02

Receptor Information
>8ine Chain v (length=404) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGGLEKKKYERGSATNYITRNKARKKLQLSLADFRRLCILKGIYPHEPKH
KKKVNKGSTAARTFYLIKDIRFLLHEPIVNKFREYKVFVRKLRKAYGKSE
WNTVERLKDNKPNYKLDHIIKERYPTFIDALRDLDDALSMCFLFSTFPRT
GKCHVQTIQLCRRLTVEFMHYIIAARALRKVFLSIKGIYYQAEVLGQPIV
WITPYAFSHDHPTDVDYRVMATFTEFYTTLLGFVNFRLYQLLNLHYPPKL
EGQAQLDSESCMEKLAALSASLARVVVDGEMSAQEEDRRKELEAQEKHKK
LFEGLKFFLNREVPREALAFIIRSFGGEVSWDKSLCIGATYDVTDSRITH
QIVDRPGQQTSVIGRCYVQPQWVFDSVNARLLLPVAEYFSGVQLPPHLSP
FVTE
Ligand information
>8ine Chain 8 (length=155) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacugcggccccggguuccucccggggcuacgccugucugagcg
ucgcu
.........................................<<<<<<.<<
.....>>>.....(.<<<......>>.............>>>..)...>>
>....<<...>><<<<<<<<<.....>>>>>>>>>...............
.....
Receptor-Ligand Complex Structure
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PDB8ine Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		R11 S13 N16 K68 R71 H75 K86 R90
Binding residue
(residue number reindexed from 1)		R11 S13 N16 K68 R71 H75 K86 R90
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0008283 cell population proliferation
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0016020 membrane
GO:0030687 preribosome, large subunit precursor
GO:0070545 PeBoW complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ine, PDBe:8ine, PDBj:8ine
PDBsum8ine
PubMed37491604
UniProtO00541|PESC_HUMAN Pescadillo homolog (Gene Name=PES1)

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