Structure of PDB 6g4w Chain u Binding Site BS02

Receptor Information
>6g4w Chain u (length=628) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSRVDQRHRASQLRKQKKEAVLAEKRQLGGKDGPPHQVLVVPLHSRISLP
EAMQLLQDGTVHLNELGNTQNFMLLCPRLKHRWFFTSARPGDLHVVLDMA
KVADTILFLLDPLEGWDSTGDYCLSCLFAQGLPTYTLAVQGISGLPLKKQ
IDTRKKLSKAVEKRFPHDKLLLLDTQQEAGMLLRQLANQKQQHLAFRDRR
AYLFAHAVDFVPSEENNLVGTLKISGYVRGQTLNVNRLLHIVGYGDFQMK
QIDAPGDPFPLNPKVLMKADPGRQESLQAEVIPDPKVPKGTSSYQAEWID
EEAEAKMLEKYKQERLEEMFPDEVDTPRDVAARIRFQKYRGLKSFRTSPW
DPKENLPQDYARIFQFQNFTNTRKSIFKEVEEKEVEGAEVGWYVTLHVSE
VPVSVVECFRQGTPLIAFSLLPHEQKMSVLNMVVRRDPGNTEPVKAKEEL
IFHCGFRRFRASPLFSQHTAADKHKLQRFLTADMALVATVYAPITFPPAS
VLLFKQKSNGMHSLIATGHLMSVDPDRMVIKRVVLSGHPFKIFTKMAVVR
YMFFNREDVLWFKPVELRTKWGRRGHIKEPLGTHGHMKCSFDGKLKSQDT
VLMNLYKRVFPKWTYDPYVPEPVPWLKS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6g4w Visualizing late states of human 40S ribosomal subunit maturation.
Resolution4.5 Å
Binding residue
(original residue number in PDB)		K517 I527 F528 Q529 Q531 W725
Binding residue
(residue number reindexed from 1)		K353 I363 F364 Q365 Q367 W561
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0034511 U3 snoRNA binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0030688 preribosome, small subunit precursor

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6g4w, PDBe:6g4w, PDBj:6g4w
PDBsum6g4w
PubMed29875412
UniProtQ2NL82|TSR1_HUMAN Pre-rRNA-processing protein TSR1 homolog (Gene Name=TSR1)

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