Structure of PDB 6c0f Chain u Binding Site BS02

Receptor Information

>6c0f Chain u (length=129) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

RIYQCHFCSSPCYPGHGIMFVRNDAKEFRFCRSKCHKAFKQRRNPRKLKW
TKAFRKAAGKELAVDSTLTFAQRRNVPVRYNRELVATTLKAMARIEEIRQ
KRERAFYKNRMRGNKEKDFLRDKKLVESN

Ligand information

InChI=1S/Zn/q+2

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Zn

Name

ZINC ION

PDB chain

6c0f Chain u Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	6c0f Modular assembly of the nucleolar pre-60S ribosomal subunit.
Resolution	3.7 Å
Binding residue (original residue number in PDB)	C6 C9 C32 C36
Binding residue (residue number reindexed from 1)	C5 C8 C31 C35
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0001671	ATPase activator activity
GO:0051117	ATPase binding

	Biological Process
GO:0032781	positive regulation of ATP-dependent activity
GO:0042254	ribosome biogenesis
GO:0042273	ribosomal large subunit biogenesis
GO:1902626	assembly of large subunit precursor of preribosome

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0030687	preribosome, large subunit precursor

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Cellular Component

External links

PDB	RCSB:6c0f, PDBe:6c0f, PDBj:6c0f
PDBsum	6c0f
PubMed	29512650
UniProt	Q07915\|RLP24_YEAST Ribosome biogenesis protein RLP24 (Gene Name=RLP24)

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