Structure of PDB 8esq Chain t Binding Site BS02

Receptor Information
>8esq Chain t (length=235) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PEVLLKKRKVNERTRKERVEQAIAKKEAQKKNRKETFKRAETFINNYRQR
ERERIRLNRSAKNKGDIFVPDETKLLFVIRIAGVKNMPPKIRKVLRLLRL
SRINNAVFVRNNKAVAQMLRIVEPYVMYGIPNLHSVRELIYKRGFGKING
QRIALSDNALIEEALGKYDVISIEDIIHEIYNVGSHFKEVTKFLWPFTLT
PVKHSLMEKKVKHFNEGRKAGYCGEEINELIKKQV
Ligand information
>8esq Chain 2 (length=150) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaaacuuucagcaacggaucucuuggcucucgcaucgaugaagaacgcag
cgaaaugcgauacguaaugugaauugcagaagaaucaucgaaucuuugaa
cgcacugcgccuuuggguucuaccaaaggcaugccuguuugagugucauu
..........................................<<<<<<.<
<.....>>>.....(.<<<......>>........>>>..)...>>>...
.<<<.>>><<<<<<<<......>>>>>>>>....................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8esq Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		F51 R53
Binding residue
(residue number reindexed from 1)		F37 R39
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:1902626 assembly of large subunit precursor of preribosome
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0030687 preribosome, large subunit precursor
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8esq, PDBe:8esq, PDBj:8esq
PDBsum8esq
PubMed36423630
UniProtP17937|RL7A_SCHPO Large ribosomal subunit protein uL30A (Gene Name=rlp7)

[Back to BioLiP]