Structure of PDB 7nac Chain t Binding Site BS02

Receptor Information
>7nac Chain t (length=285) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LNSNPEILLRKRRNADRTRIERQELAKKKREEQIKKKRSNKNKFVRAESI
VAKTLATSREKERIKRVSILEDKKAKNETQHIASGKDFILKITEGLIREK
TTYDGKPALLFIVRVRGPLAVNIPNKAFKILSLLRLVETNTGVFVKLTKN
VYPLLKVIAPYVVIGKPSLSSIRSLIQKRGRIIYKEPHEIVLNDNNIVEE
QLGDHGIICVEDIIHEIATMGESFSVCNFFLQPFKLNREVSGFGSLNRLR
KIKQREAESRTRQFSNAATAPVIEVDIDSLLAKLN
Ligand information
>7nac Chain 2 (length=158) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaacuuucaacaacggaucucuugguucucgcaucgaugaagaacgcagc
gaaaugcgauacguaaugugaauugcagaauuccgugaaucaucgaaucu
uugaacgcacauugcgccccuugguauuccagggggcaugccuguuugag
cgucauuu
.........................................<<<<<<.<<
.....>>>.....(.<<<......>>..............>>>..)...>
>>....<<.....>><<<<<<<<<....>>>>>>>>>.............
........
Receptor-Ligand Complex Structure
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PDB7nac Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Resolution3.04 Å
Binding residue
(original residue number in PDB)
K54 F55 R57 A152
Binding residue
(residue number reindexed from 1)
K43 F44 R46 A120
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0042134 rRNA primary transcript binding
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000465 exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0022625 cytosolic large ribosomal subunit
GO:0030687 preribosome, large subunit precursor

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7nac, PDBe:7nac, PDBj:7nac
PDBsum7nac
PubMed36482249
UniProtP40693|RLP7_YEAST Ribosome biogenesis protein RLP7 (Gene Name=RLP7)

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