Structure of PDB 5gak Chain q Binding Site BS02
Receptor Information
>5gak Chain q (length=154) Species:
4932
(Saccharomyces cerevisiae) [
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EEHTFETADAGSSATYPMQCSALRKNGFVVIKSRPCKIVDMSTSKTGKHG
HAKVHLVAIDIFTGKKLEDLSPSTHNMEVPVVKRNEYQLLDIDDGFLSLM
NMDGDTKDDVKAPEGELGDSLQTAFDEGKDLMVTIISAMGEEAAISFKEA
ARTD
Ligand information
>5gak Chain B (length=77) [
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ggagcgguaguucagucgguuagaauaccugccugucacgcagggggucg
cggguucgagucccguccguuccgcca
<<<<<<<..<<<<.........>>>>.<<<<<.......>>>>>.....<
<<<<.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
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PDB
5gak
Structure of the hypusinylated eukaryotic translation factor eIF-5A bound to the ribosome.
Resolution
3.88 Å
Binding residue
(original residue number in PDB)
R27 F31 X51 R87 K151
Binding residue
(residue number reindexed from 1)
R24 F28 X48 R84 K148
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0003743
translation initiation factor activity
GO:0003746
translation elongation factor activity
GO:0005515
protein binding
GO:0043022
ribosome binding
Biological Process
GO:0002182
cytoplasmic translational elongation
GO:0002184
cytoplasmic translational termination
GO:0006412
translation
GO:0006413
translational initiation
GO:0006414
translational elongation
GO:0006452
translational frameshifting
GO:0045901
positive regulation of translational elongation
GO:0045905
positive regulation of translational termination
GO:0045948
positive regulation of translational initiation
GO:0072344
rescue of stalled ribosome
GO:0097622
cytoplasmic translational elongation through polyproline stretches
GO:0140708
CAT tailing
GO:1903272
positive regulation of cytoplasmic translational elongation through polyproline stretches
Cellular Component
GO:0005737
cytoplasm
GO:0005739
mitochondrion
GO:0005829
cytosol
GO:0048471
perinuclear region of cytoplasm
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Molecular Function
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Cellular Component
External links
PDB
RCSB:5gak
,
PDBe:5gak
,
PDBj:5gak
PDBsum
5gak
PubMed
26715760
UniProt
P23301
|IF5A1_YEAST Eukaryotic translation initiation factor 5A-1 (Gene Name=HYP2)
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