Structure of PDB 8wib Chain p Binding Site BS02

Receptor Information
>8wib Chain p (length=88) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALTAEQKKEILGQYGLHDTDTGSPEAQVALLTKRIQDLTEHLKVHKHDHH
SRRGLLLLVGRRRRLLKYVAQVDVARYRSLIERLGLRR
Ligand information
>8wib Chain a (length=1515) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuggagaguuugauccuggcucaggacgaacgcuggcggcgugcuuaaca
caugcaagucgaacggaaaggcccuuucggggguacucgaguggcgaacg
ggugaguaacacgugggugaucugcccugcacuuugggauaagccuggga
aacugggucuaauaccgaauacacccugcuggucgcauggccugguaggg
gaaagcuuuugcggugugggaugggcccgcggccuaucagcuuguuggug
gggugauggccuaccaaggcgacgacggguagccggccugagagggugac
cggccacacugggacugagauacggcccagacuccuacgggaggcagcag
uggggaauauugcacaaugggcgcaagccugaugcagcgacgccgcguga
gggaugacggccuucggguuguaaaccucuuucagcacagacgaagcgca
agugacgguaugugcagaagaaggaccggccaacuacgugccagcagccg
cgguaauacguaggguccgagcguuguccggaauuacugggcguaaagag
cucguaggugguuugucgcguuguucgugaaaacucacagcuuaacugug
ggcgugcgggcgauacgggcagacuagaguacugcaggggagacuggaau
uccugguguagcgguggaaugcgcagauaucaggaggaacaccgguggcg
aaggcgggucucugggcaguaacugacgcugaggagcgaaagcgugggga
gcgaacaggauuagauacccugguaguccacgccguaaacgguggguacu
agguguggguuuccuuccuugggauccgugccguagcuaacgcauuaagu
accccgccuggggaguacggccgcaaggcuaaaacucaaaggaauugacg
ggggcccgcacaagcggcggagcauguggauuaauucgaugcaacgcgaa
gaaccuuaccuggguuugacaugcacaggacgccggcagagaugucgguu
cccuuguggccugugugcagguggugcauggcugucgucagcucgugucg
ugagauguuggguuaagucccgcaacgagcgcaacccuugucucauguug
ccagcacguuaugguggggacucgugagagacugccggggucaacucgga
ggaagguggggaugacgucaagucaucaugccccuuauguccagggcuuc
acacaugcuacaauggccgguacaaagggcugcgaugccgugagguggag
cgaauccuuucaaagccggucucaguucggaucggggucugcaacucgac
cccgugaagucggagucgcuaguaaucgcagaucagcaacgcugcgguga
auacguucccgggccuuguacacaccgcccgucacgucaugaaagucggu
aacacccgaagccgguggccuaacccuuguggagggagccgucgaaggug
ggaucggcgauugggacgaagucguaacaagguagccguaccggaaggug
cggcuggaucaccuc
.....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<
<.<<<..<<<..<<.<..<<<<<<<....>>>>>.>>>..>>>>>.....
.<<........<<<<<<<..<<...<<<<<<<<<<<<.....<<<<<<..
..>>>>>>......>>>>.....<<<<<<<<<<<<..>>>>>.>>>>>>>
....<<....>>>>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<
<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...
>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>
>>.........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<
<<......<<<<....>>>>.....>>>>...<.<<<<<......<<...
.>>.......>>>>>....>..<<<<<(((...<<<<<.....<<.)))>
>.......>>>>>>>>>>..>>>>>>>>>..........<<<((.....<
<<<...<<<.<<<<<<<.<<<<<<<<<<.....<<<<<<<.....>>>>>
>>...>>>>>>>..>>>>>>>>>>...<<<<<<<<...<<<<<<<....<
<<<<<<<<..<<<......>>>.....>>>>>>>>>...........<<.
...>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<...
<<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<<<<.
.<<<<<<<<<<<<.......>>>>>>>>>>>>...<<..))>>.....>>
>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<
.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>..
........<<<<<<<......<<<<<<<...<<<<<<<....>>>>>>>.
<<.....>>.>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<.
...>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<....
<<..<<<......>>>>>.....>>>>>>.....<<<<<.....>>>>>.
.......>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>
.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>..>
>....>>>......>>>>>>>......<....<<<<<<<........>>>
>>>>....>.....>>>>>>....<<<<<<<..........>>>>>>>..
....>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<
..<<<<....<.<<<<..<<<..<<.....>>.>>>.>>>>.>...>>>>
..>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>
>>>>>..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8wib Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		K8 D21 T22 G23 Q28 R35 H42 H48 D49 H51 S52 R54 L58 R65 Y69
Binding residue
(residue number reindexed from 1)		K7 D20 T21 G22 Q27 R34 H41 H47 D48 H50 S51 R53 L57 R64 Y68
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8wib, PDBe:8wib, PDBj:8wib
PDBsum8wib
PubMed38245551
UniProtA0QVQ3|RS15_MYCS2 Small ribosomal subunit protein uS15 (Gene Name=rpsO)

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