Structure of PDB 8q5i Chain p Binding Site BS02

Receptor Information

>8q5i Chain p (length=232) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

NPLFESTPKNFGIGQSIQPKRNLSRFVKWPEYVRLQRQKKILSLRLKVPP
SIAQFSQTLDKNTAAQAFKLLNKYRPETSAEKKERLTKEAAAIAEGKTAK
DVSPKPVVVKYGLNHVVSLIENKKAKLVLIANDVDPIELVVFLPALCKKM
GVPYAIVKGKARLGTLVHKKTSAVAALTEVNSADEAELSKLISTINANYI
EKYEENRKHWGGGIMGSKANDKIAKKAKAAAA

Ligand information

>8q5i Chain 4 (length=158) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

aaacuuucaacaacggaucucuugguucucgcaucgaugaagaacgcagc
gaaaugcgauacguaauaugaauugcagauauucgugaaucaucgaaucu
uugaacgcacauugcgcccucugguauuccggagggcaugccuguuugag
cgucguuu

.........................................<<<<<<.((
.....>>>.....<.<<<<.....))............>>.>>..>...>
>>....<<.....>><<<<<<<<<....>>>>>>>>>.............
........

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8q5i Structural characterization of cephaeline binding to the eukaryotic ribosome using Cryo-Electron Microscopy
Resolution	2.45 Å
Binding residue (original residue number in PDB)	Y56 V57 Q60 R61 K64 K85 K182 R186
Binding residue (residue number reindexed from 1)	Y32 V33 Q36 R37 K40 K61 K158 R162

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding

	Biological Process
GO:0000470	maturation of LSU-rRNA
GO:0042254	ribosome biogenesis

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Cellular Component

External links

PDB	RCSB:8q5i, PDBe:8q5i, PDBj:8q5i
PDBsum	8q5i
PubMed
UniProt	A0A8H6C337

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