Structure of PDB 7pzy Chain p Binding Site BS02

Receptor Information
>7pzy Chain p (length=238) Species: 237561 (Candida albicans SC5314) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NPLFESTPKNFGIGQSIQPKRNLSRFVKWPEYVRLQRQKKILSLRLKVPP
SIAQFSQTLDKNTAAQAFKLLNKYRPETSAEKKERLTKEAAAIAEGKTAK
DVSPKPVVVKYGLNHVVSLIENKKAKLVLIANDVDPIELVVFLPALCKKM
GVPYAIVKGKARLGTLVHKKTSAVAALTEVNSADEAELSKLISTINANYI
EKYEENRKHWGGGIMGSKANDKIAKKAKAAAAAVSTSN
Ligand information
>7pzy Chain 4 (length=158) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaacuuucaacaacggaucucuugguucucgcaucgaugaagaacgcagc
gaaaugcgauacguaauaugaauugcagauauucgugaaucaucgaaucu
uugaacgcacauugcgcccucugguauuccggagggcaugccuguuugag
cgucguuu
.........................................<<<<<<.((
.....>>>.....<.<<<<.....))............>>.>>..>...>
>>....<<.....>><<<<<<<<<....>>>>>>>>>.............
........
Receptor-Ligand Complex Structure
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PDB7pzy E-site drug specificity of the human pathogen Candida albicans ribosome.
Resolution2.32 Å
Binding residue
(original residue number in PDB)		Y56 V57 Q60 R61 K64 K85 R186
Binding residue
(residue number reindexed from 1)		Y32 V33 Q36 R37 K40 K61 R162
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003723 RNA binding
Biological Process
GO:0000470 maturation of LSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7pzy, PDBe:7pzy, PDBj:7pzy
PDBsum7pzy
PubMed35613268
UniProtQ5ANA1|RL8B_CANAL Large ribosomal subunit protein eL8B (Gene Name=RPL8B)

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