Structure of PDB 6olf Chain p Binding Site BS02

Receptor Information
>6olf Chain p (length=105) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQ
TKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKG
QVIQF
Ligand information
>6olf Chain v (length=76) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugcccgguagccccgaagguagagcaggggauuccgaauccccguguccu
ugguucgauuccgaguccgggcacca
..<<<<<..<<............>>.<<<<<<.....>>>>>>......<
.<.........>..>.>>>>>.....
Receptor-Ligand Complex Structure
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PDB6olf Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		G37 K38 Y41 K53 I55 F56
Binding residue
(residue number reindexed from 1)		G36 K37 Y40 K52 I54 F55
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005886 plasma membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:6olf, PDBe:6olf, PDBj:6olf
PDBsum6olf
PubMed31160784
UniProtP83881|RL36A_HUMAN Large ribosomal subunit protein eL42 (Gene Name=RPL36A)

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