Structure of PDB 8q5i Chain o Binding Site BS02

Receptor Information

>8q5i Chain o (length=226) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

AQQKTAEERAAAKKVRKAANKEKRKVIFDRAAAYQKEYTEAERSVIKAKR
DAKASNSYYVDAQPKLVFVVRIKGINKIPPKPRKVLQLLRLTQINAGVFV
RLTKATSELIKLAEPYVAYGYPSLSTIRQLVYKRGFGKVNKQRIALSDNA
IIEANLGKFNILSIEDLIHEIYTVGPNFKQVSNFLWPFKLSNPNGGFRAR
KFQHFIQGGDTGNREQFINALVKQMN

Ligand information

>8q5i Chain 3 (length=121) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gguugcggccauaucuagcagaaagcaccguuccccguucgaucaaccgu
aguuaagcugcuaagagcaauaccgaguaguguagugggagaccauacgc
gaaacuauugugcugcaaucu

<<<<<<<<<....<<<<<<<<.....<<.<<..............>>...
.>>....>>>>>>.>><<<<<<.......<<<<<..<<....>>.>>>>>
.....>>>>>>>>>>>>>>>.

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8q5i Structural characterization of cephaeline binding to the eukaryotic ribosome using Cryo-Electron Microscopy
Resolution	2.45 Å
Binding residue (original residue number in PDB)	K126 E129 R215 F217 H219 I221 Q222
Binding residue (residue number reindexed from 1)	K111 E114 R200 F202 H204 I206 Q207

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit

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Cellular Component

External links

PDB	RCSB:8q5i, PDBe:8q5i, PDBj:8q5i
PDBsum	8q5i
PubMed
UniProt	A0A8H6BVN2

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