Structure of PDB 8jdm Chain o Binding Site BS02
Receptor Information
>8jdm Chain o (length=86) Species:
9606
(Homo sapiens) [
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TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSA
KAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPK
Ligand information
>8jdm Chain F (length=156) [
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cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacuugcggccccggguuccucccggggcuacgccugucugagc
gucgcu
.........................................<<<<<<.<<
.....>>>.....(.<<<.(....>>.........)...>>>..)...>>
>....<<....>><<<<<<<<<.....>>>>>>>>>..............
......
Receptor-Ligand Complex Structure
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PDB
8jdm
Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Resolution
2.67 Å
Binding residue
(original residue number in PDB)
R20 R21 G23 Y39 T59 G60 G62 R63 M64 R65 H66 L67 R72 F74 H76 R79 E80 T82 P84 K85 K87
Binding residue
(residue number reindexed from 1)
R19 R20 G22 Y38 T58 G59 G61 R62 M63 R64 H65 L66 R71 F73 H75 R78 E79 T81 P83 K84 K86
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0003735
structural constituent of ribosome
GO:0019843
rRNA binding
GO:0046872
metal ion binding
GO:0097371
MDM2/MDM4 family protein binding
GO:1990948
ubiquitin ligase inhibitor activity
Biological Process
GO:0002181
cytoplasmic translation
GO:0006412
translation
GO:1901798
positive regulation of signal transduction by p53 class mediator
Cellular Component
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0005840
ribosome
GO:0022625
cytosolic large ribosomal subunit
GO:0022626
cytosolic ribosome
GO:1990904
ribonucleoprotein complex
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Molecular Function
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Cellular Component
External links
PDB
RCSB:8jdm
,
PDBe:8jdm
,
PDBj:8jdm
PDBsum
8jdm
PubMed
37992713
UniProt
P61927
|RL37_HUMAN Large ribosomal subunit protein eL37 (Gene Name=RPL37)
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