Structure of PDB 7jsw Chain o Binding Site BS02

Receptor Information

>7jsw Chain o (length=116) Species: 83333 (Escherichia coli K-12)

DKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAA
STVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHG
RVQALADAAREAGLQF

Ligand information

>7jsw Chain 2 (length=120)

ugccuggcggccguagcgcgguggucccaccugaccccaugccgaacuca
gaagugaaacgccguagcgccgaugguaguguggggucuccccaugcgag
aguagggaacugccaggcaa

<<<<<<<<<<.....<<<<<<<<....<<<<<<<.............>>>
>..>>>...>>>>>>.>>.<<.......<<<<<<<<...>>>>>>>>...
....>>...>>>>>>>>>>.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7jsw ArfB can displace mRNA to rescue stalled ribosomes.
• Resolution: 3.8 Å
• Binding residue (original residue number in PDB): R15 R25 V27 H29 R30 T31 P32 R33 H34 Q38 G44 S45 E46 V47 A50 Y64 G66 N67 K68 H100 R102
• Binding residue (residue number reindexed from 1): R14 R24 V26 H28 R29 T30 P31 R32 H33 Q37 G43 S44 E45 V46 A49 Y63 G65 N66 K67 H99 R101

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7jsw, PDBe:7jsw, PDBj:7jsw
• PDBsum: 7jsw
• PubMed: 33144582
• UniProt: P0C018|RL18_ECOLI Large ribosomal subunit protein uL18 (Gene Name=rplR)