Structure of PDB 6wdi Chain o Binding Site BS02

Receptor Information

>6wdi Chain o (length=116) Species: 562 (Escherichia coli)

DKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAA
STVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHG
RVQALADAAREAGLQF

Ligand information

>6wdi Chain 2 (length=120)

ugccuggcggccguagcgcgguggucccaccugaccccaugccgaacuca
gaagugaaacgccguagcgccgaugguaguguggggucuccccaugcgag
aguagggaacugccaggcaa

<<<<<<<<<<.....<<<<<<<<....<<<<<<<.............>>>
>..>>>...>>>>>>.>>.<<........<<<<<<<...>>>>>>>....
....>>...>>>>>>>>>>.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6wdi Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading.
• Resolution: 4.0 Å
• Binding residue (original residue number in PDB): K3 R15 H29 T31 P32 R33 H34 K56 Y64 N67 K68 H100 G101
• Binding residue (residue number reindexed from 1): K2 R14 H28 T30 P31 R32 H33 K55 Y63 N66 K67 H99 G100

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6wdi, PDBe:6wdi, PDBj:6wdi
• PDBsum: 6wdi
• PubMed: 32612237
• UniProt: P0C018|RL18_ECOLI Large ribosomal subunit protein uL18 (Gene Name=rplR)