Structure of PDB 6ogg Chain o Binding Site BS02

Receptor Information

>6ogg Chain o (length=116) Species: 562 (Escherichia coli)

DKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAA
STVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHG
RVQALADAAREAGLQF

Ligand information

>6ogg Chain 2 (length=120)

ugccuggcggccguagcgcgguggucccaccugaccccaugccgaacuca
gaagugaaacgccguagcgccgaugguaguguggggucuccccaugcgag
aguagggaacugccaggcaa

<<<<<<<<<<.....<<<<<<<<....<<<<<<<.............>>>
>..>>>...>>>>>>.>>.<<.......<<<<<<<<...>>>>>>>>...
....>>...>>>>>>>>>>.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6ogg Extensive ribosome and RF2 rearrangements during translation termination.
• Resolution: 4.2 Å
• Binding residue (original residue number in PDB): K3 R15 V27 H29 R30 T31 P32 R33 H34 S45 V47 K56 Y64 N67 K68 Q98 H100 G101 R102
• Binding residue (residue number reindexed from 1): K2 R14 V26 H28 R29 T30 P31 R32 H33 S44 V46 K55 Y63 N66 K67 Q97 H99 G100 R101

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6ogg, PDBe:6ogg, PDBj:6ogg
• PDBsum: 6ogg
• PubMed: 31513010
• UniProt: P0C018|RL18_ECOLI Large ribosomal subunit protein uL18 (Gene Name=rplR)