Structure of PDB 6fyx Chain o Binding Site BS02

Receptor Information
>6fyx Chain o (length=529) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FRPENAIKRADELISVGEKQAALQSLHDFITARRIRWATPSTVEPVVFKF
LEIGVELKKGKLLKDGLHQYKKLIQGSTEGLVSVGAVARKFIDLVESKIA
SEQTRADELQKQEIDAITSWLRFTWESYRAVLDLLRNNALLEITYSGVVK
KTMHFCLKYQRKNEFKRLAEMLRQHLDAANYQQSDADTLQRYLDQRFQQV
DVSVKLELWHEAYRSIEDVFHLMKISKRAPKPSTLANYYENLVKVFFVSG
DPLLHTTAWKKFYKLYSTNPRATEEEFKTYSSTIFLSAISTQLDEIPSIG
YDPHLRMYRLLNLDAKPTRKEMLQSIIEDESIYGKVDEELKELYDIIEVN
FDVDTVKQQLENLLVKLSSKTYFSQYIAPLRDVIMRRVFVAASQKFTTVS
QSELYKLATLPAPLDLSAWDIEKSLLQAAVEDYVSITIDHESAKVTFAKD
PAAKKARIEEVRKRRYEEAIARRKEEIANAERQKRAQELAEATRKQREIE
EAAAKKSAGRTAGGSSPATPATPATPATP
Ligand information
>6fyx Chain 3 (length=31) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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...............................
Receptor-Ligand Complex Structure
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PDB6fyx Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		A37 R38 R39 R41 W42 K77 L78 Q80
Binding residue
(residue number reindexed from 1)		A32 R33 R34 R36 W37 K72 L73 Q75
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
Biological Process
GO:0001732 formation of cytoplasmic translation initiation complex
GO:0002183 cytoplasmic translational initiation
GO:0002188 translation reinitiation
GO:0006412 translation
GO:0006413 translational initiation
Cellular Component
GO:0000131 incipient cellular bud site
GO:0005737 cytoplasm
GO:0005852 eukaryotic translation initiation factor 3 complex
GO:0010494 cytoplasmic stress granule
GO:0016282 eukaryotic 43S preinitiation complex
GO:0033290 eukaryotic 48S preinitiation complex
GO:0043614 multi-eIF complex
GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e
GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6fyx, PDBe:6fyx, PDBj:6fyx
PDBsum6fyx
PubMed30475211
UniProtP38249|EIF3A_YEAST Eukaryotic translation initiation factor 3 subunit A (Gene Name=RPG1)

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