Structure of PDB 8ury Chain n Binding Site BS02

Receptor Information
>8ury Chain n (length=177) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLD
NAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFE
RLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRG
LDITITTTAKSDEEGRALLAAFDFPFR
Ligand information
>8ury Chain a (length=2880) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguuaagcgacuaagcguacacgguggaugcccuggcagucagaggcgau
gaaggacgugcuaaucugcgauaagcgucgguaaggugauaugaaccguu
auaaccggcgauuuccgaauggggaaacccaguguguuucgacacacuau
cauuaacugaauccauagguuaaugaggcgaaccgggggaacugaaacau
cuaaguaccccgaggaaaagaaaucaaccgagauucccccaguagcggcg
agcgaacggggagcagcccagagccugaaucaguguguguguuaguggaa
gcgucuggaaaggcgcgcgauacagggugacagccccguacacaaaaaug
cacaugcugugagcucgaugaguagggcgggacacgugguauccugucug
aauauggggggaccauccuccaaggcuaaauacuccugacugaccgauag
ugaaccaguaccgugagggaaaggcgaaaagaaccccggcgaggggagug
aaaaagaaccugaaaccguguacguacaagcagugggagcacgcuuaggc
gugugacugcguaccuuuuguauaaugggucagcgacuuauauucuguag
caagguuaaccgaauaggggagccgaagggaaaccgagucuuaacugggc
guuaaguugcaggguauagacccgaaacccggugaucuagccaugggcag
guugaagguuggguaacacuaacuggaggaccgaaccgacuaaugaaaaa
uuagcggaugacuuguggcugggggugaaaggccaaucaaaccgggagau
agcugguucuccccgaaagcuauuuagguagcgccucgugaauucaucuc
cggggguagagcacuguuucggcaagggggucaacccgacuuaccaaccc
gaugcaaacugcgaauaccggagaauguuaucacgggagacacacggcgg
ggcuaacguccgucgugaagagggaaacaacccagaccgccagcuaaggu
cccaaagucaugguuaagugggaaacgaugugggaaggcccagacagcca
ggauguuggcuuagaagcagccaucauuuaaagaaagcguaauagcucac
uggucgagucggccugcgcggaagauguaacggggcuaaaccaugcaccg
aagcugcggcagcgacgcuuaugcguuguuggguaggggagcguucugua
agccugcgaaggugugcugugaggcaugcuggagguaucagaagugcgaa
ugcugacauaaguaacgauaaagcgggugaaaagcccgcucgccggaaga
ccaaggguuccuguccaacguuaaucggggcagggugagucgaccccuaa
ggcgaggccgaaaggcguagucgaugggaaacagguuaauauuccuguac
uugguguuacugcgaaggggggacggagaaggcuauguuggccgggcgac
gguugucccgguuuaagcguguaggcugguuuuccaggcaaauccggaaa
aucaaggcugaggcgugaugacgaggcacuacggugcugaagcaacaaau
gcccugcuuccaggaaaagccucuaagcaucagguaacaucaaaucguac
cccaaaccgacacgguggucagguagagaauaccaaggcgcuugagagaa
cucgggugaaggaacuaggcaaaauggugccguaacuucgggagaaggca
cgcugauauguaggugaggucccucgcggauggagcugaaaucagucgaa
gauaccagcuggcugcaacuguuuauuaaaaacacagcacugugcaaaca
cgaaaguggacguauacggugugacgccucccggugccggaagguuaauu
gaugggguuagcgcaagcgaagcucuugaucgaagccccgguaaacggcg
gccgaacaaacgguccuaagguagcgaaauccuugucggguaaguuccga
cugcacgaauggcguaaugauggccaggcugucuccacccgagacucagu
gaaauugaacucgcugugagaugcaguguacccgcggcaagacggaaaga
ccccguaaccuuacuauagcuugacacugaacauugagccuugaugugua
ggauaggugggaggcuuugaaguguggacgccagucugcauggagccgac
cuugaaauaccacccuuuaauguuugauguucuaacguugacccguaauc
cggguugcggacagugucugguggguaguuugacugggcggucuccuccu
aaagaguaacggaggagcacgaagguuggcuaauccuggucggacaucag
gagguuagugcaauggcauaagccagcuugacugcgagcgugacggcgcg
agcaggugcgaaagcaggucauagugauccggugguucugaauggaaggg
ccaucgcucaacggauaaaagguacuccgggauaacaggcgauaccgccc
aagaguucauaucgacggcgguguuuggcacucggucggcucaucacauc
cuggggcugaaguaggucccaaggguauggcguucgccauuuaaaguggu
acgcgagcggguuuagaacgucgugagacagucggucccuaucugccgug
ggcgcuggagaacugaggggggcugcuccuaguacgagaggaccggagug
gacgcaucacugguguucggguugucaugccaauggcacugcccgguagc
uaaaugcggaagagauaagugcugaaagcaucuaagcacgaaacuugccc
cgagaugaguucucccugacccuuuaaggguccugaaggaacguugaaga
cgacgacguugauaggccggguguguaagcgcagcgaugcguugagcuaa
ccgguacuaaugaaccgugaggcuuaaccu
<<<<<<<<......<<<<<<<<<<<.....<<..<<<<<<<<<<<<<...
...<<<<<<.[..(((.>>>.....<<<<<<<..<<<)))..].>>>...
...>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>
>......>>>>>.>.........<<....>>..<<<<<<.....<<....
.>>....>>>>>>..<<<..<<<<.<....<<<<<<<<<<<<<.<<<...
<<<<<......>>>>>((......<<<.....))>>>...>>>...>>>>
>>>>>>>>>..>>>>>........<<<<<<<<.........>>>>>>>>.
.....<<<<<..((((>>>>>..>>>......>>.>>>>>>>.>>.....
..........<<....>>....>>.........<<<<.....>>>>....
..............>>>>>>>>>>>.......<<<<..<<<<<<....>>
>>>>..>>>>...<............>.<<<<<<....<<<<<<<<<<<<
<..<<<...<<.....>>...>>>...<<....>>..<<<<.....>>>>
.....>>>>>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<
<<....<<<<<<......>>>>>>.....>>>...<<<.<<<<<.....>
>>>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>....
..>.>>..<<<<<<....<<<<<....>>>>>.<<<<<<<<...<<<<<<
<<<.....<<<...<<<.<<<<...<<.<<<<.....>>>>..>>...>>
>>.>>>..>>.>.....>>>>>>>.>>...>>>>>>>.>...<<<<<<<<
<.......>>>>>>>>>....<<<......>>>...<<<<.<<<...<<<
(((.....<<<<<<...........<<..<<<<<..<<........<<<<
<.<<...<<<<.......>>>>...>>........<<<......>>>..>
>>>>....>>..>>>>>.>>...........))).....>>>>>>.>>>.
..>>>>>>><<<<<<<<<....>>>>>>>>>....>>>>>>..<<<<<..
.<<<......<<<<<<<<....>>>>>>>>...>>>..>>>>>.......
.>>>>>><......<<.....<<<<<<.......>>>>>><<<<....<<
<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<.<<<...
<<<...<<<....>>>...>>>...>>>..<<<<<........>>>>>))
<<<<<<<<<<<<<...<<<<....<<<<..<<<..<<<<<<<<<<<....
[[[...>>>>>><<..<<<<...<<<<<<<<<<<<.<<.....>>>>>>>
>>>..>>>>...>>>>...>><..<<<<<....>>>>>...>>>>>>...
>>>...>>>>.........>>>>...>>....>>>>>>>>>>>.>>>..>
>.....<<.....>>>>>>>.<<<<.....>>>>..>>>>..<<<<....
<<<<<<<<.<<.........<.....<<<<<...............>>>>
><<<<<<.....<<<...<<<<.....>>>>...>>>...>>>>>>....
........<<<<<<<<<..<<<.........>>>..<<<<<<<.....<<
<....>>>.......>>>>>>>.<<<<<.<<..<<<<<<<..<<<....<
...<<<<<..<<....>>...>>>>>.>......>>>>>>>>..>>>>..
<<<<......>>>>.........<..........<<<<<<.....>>>>>
>....>....>>>>>..>>.>>>>>>>..>..>>.>>>>>>>>.>>>>>>
.....>.....<<<<<.......>>>>>..<<<<<<<<.<<<.<<.....
.<.<<..<<<..<<<<<.<<<.<<<<<.<<<<<<<<<<<.<<<<......
.....<<<<<..<<.......<<<<<<<<....>>>>>>>>....>>...
.........>>>>>..>>>>.>>>>>>>>>>>...<<<.<<<<<<.....
>>>>>>>>>....>>>>>.>>>..>>>>>..<<<<....>>>><<<<<<.
..........>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>
>>.....<<...(((>>....>>>>>>>...<<<<..<<<<....>>>>.
.>>>>.<<<....>>>.>>))).......<<<<<<<.<<..))))..>>>
>>>>>>..............>>>....>>>........<<...<<<<<<.
..<<.......>>...>>>>>>.....>>......<<.<<.<<<<<<..<
<<<<<<<<......>>>>>>>..>>.<<<<<....>>>>>.....>>>>>
..>...>>.>>....<.<<<<<....>>>.>>>....>>..>>>>>>>>>
>>....<<<<<<<...<<<<..<<<<<<<...............>>>>>>
>.<<<<<...<<<<...<<<<<<<<<<<]]].>>>>>>..>>>>>...>>
>>.>>>>>...<<<....<<<<<...........>>>>>....>>>.>>>
>.......>>>>>>>..<<<<<.....>>>>><....<<..<<<<<....
...>>>>>....<<<<<<<<..<<....<<<<<....>>>>>...>>...
>>>>>.>>>.....>>..>..>>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ury Structural basis of RfaH-mediated transcription-translation coupling
Resolution3.1 Å
Binding residue
(original residue number in PDB)
K33 T35 N37 M38 G39 G41 T68 A70 R71 K72 V74 G76 F77 I79 I85 K88 S121 D123 R125 N127 S129 M130 G131 R133 G151 L152 D153 T155 T157
Binding residue
(residue number reindexed from 1)
K32 T34 N36 M37 G38 G40 T67 A69 R70 K71 V73 G75 F76 I78 I84 K87 S120 D122 R124 N126 S128 M129 G130 R132 G150 L151 D152 T154 T156
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8ury, PDBe:8ury, PDBj:8ury
PDBsum8ury
PubMed39117885
UniProtA0A140N5A3

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