Structure of PDB 7uph Chain n Binding Site BS02

Receptor Information

>7uph Chain n (length=116) Species: 562 (Escherichia coli)

DKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAA
STVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHG
RVQALADAAREAGLQF

Ligand information

>7uph Chain J (length=118)

gccuggcggccguagcgcgguggucccaccugaccccaugccgaacucag
aagugaaacgccguagcgccgaugguaguguggggucuccccaugcgaga
guagggaacugccaggca

<<<<<<<<........<<<<<<.....<<.<<...............>>.
..>>....>>>>>>....<<.......<<<<<<<<...>>>>>>>>....
...>>....>>>>>>>>.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7uph Three-dimensional structure-guided evolution of a ribosome with tethered subunits.
• Resolution: 4.18 Å
• Binding residue (original residue number in PDB): K2 K3 R29 R32 Y35 Q37 I39 G43 S44 K62 Y63 N66 K67 F96 Q97 R101
• Binding residue (residue number reindexed from 1): K2 K3 R29 R32 Y35 Q37 I39 G43 S44 K62 Y63 N66 K67 F96 Q97 R101

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7uph, PDBe:7uph, PDBj:7uph
• PDBsum: 7uph
• PubMed: 35836020
• UniProt: P0C018|RL18_ECOLI Large ribosomal subunit protein uL18 (Gene Name=rplR)