Structure of PDB 7r6q Chain n Binding Site BS02

Receptor Information
>7r6q Chain n (length=425) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRIKKKNTRGNARNFITRSQAVRKLQVSLADFRRLCIFKGIYPREPRNKK
KANKGSTAPTTFYYAKDIQYLMHEPVLAKFREHKTFARKLTRALGRGEVS
SAKRLEENRDSYTLDHIIKERYPSFPDAIRDIDDALNMLFLFSNLPSTNQ
VSSKIINDAQKICNQWLAYVAKERLVRKVFVSIKGVYYQANIKGEEVRWL
VPFKFPENIPSDVDFRIMLTFLEFYSTLLHFVLYKLYTDSGLIYPPKLDL
KKDKIISGLSSYILESRYDSPVASLFSAFVFYVSREVPIDILEFLILSCG
GNVISEAAMDQIIDMSKVTHQIVDRPVLKNKVAGRTYIQPQWIFDCINKG
ELVPANKYLPGEALPPHLSPWGDAIGYDPTAPKKLKMIMMSNKQKKLYKK
MKYSNAKKEEQAENLKKKKKQIAKQ
Ligand information
>7r6q Chain 2 (length=57) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugaacgcacauugcgccccuugguauuccagggggcaugccuguuugagc
gucauuu
.....<<<...>>><<<<<<<<<....>>>>>>>>>..............
.......
Receptor-Ligand Complex Structure
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PDB7r6q Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Resolution2.98 Å
Binding residue
(original residue number in PDB)
R2 R9 G10 N11 N14 R47 Q69 H73 T85 R88 K89
Binding residue
(residue number reindexed from 1)
R2 R9 G10 N11 N14 R47 Q69 H73 T85 R88 K89
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030687 preribosome, large subunit precursor
GO:0070545 PeBoW complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7r6q, PDBe:7r6q, PDBj:7r6q
PDBsum7r6q
PubMed36482249
UniProtP53261|PESC_YEAST Pescadillo homolog (Gene Name=NOP7)

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