Structure of PDB 5gmk Chain n Binding Site BS02

Receptor Information
>5gmk Chain n (length=299) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FTKSELKRRRKTRKGDGPWGSWSPKKVIRNYPGHPEGTTALKFLPKTGHL
ILSGGNDHTIKIWDFECLRDFQGHNKPIKALRFTEDCQSFLSSSFDRSVK
IWDTETGKVKTRLHLNSTPADVESRPTNPHEFIVGLSNSKILHYDDVQTY
DHHLSSILALKYFPDGSKFISSSEDKTVRIWENQINVPIKQISDTASMPF
LNVHPNYFCAQSMDNRIYSFSKYKRHPKKIHSSAGYGISLAFSGDGRYIC
SGDSKSRLFTWDWNTSRLLIPGNKPITQVDWHPSKVICSGAAGKIYVCD
Ligand information
>5gmk Chain L (length=127) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acgaaucucuuugccuuuuggcuuagaucaaguguaguaucuguucuuug
uaacaacuaaugaccucagaggcucaauuuguuacaauacauuuuuuggc
accgcgacccucgcacuuguggagucg
................................................<<
<<<<<<.<...<.<<<<.>>>>.>..>.>>>>>>>>..............
..<<...<<...........>>...>>
Receptor-Ligand Complex Structure
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PDB5gmk Structure of a yeast catalytic step I spliceosome at 3.4 angstrom resolution
Resolution3.4 Å
Binding residue
(original residue number in PDB)		I324 V326
Binding residue
(residue number reindexed from 1)		I185 V187
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000386 second spliceosomal transesterification activity
GO:0003729 mRNA binding
GO:0005515 protein binding
Biological Process
GO:0000348 mRNA branch site recognition
GO:0000350 generation of catalytic spliceosome for second transesterification step
GO:0000389 mRNA 3'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0034399 nuclear periphery
GO:0071013 catalytic step 2 spliceosome

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Biological Process
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Cellular Component
External links
PDB RCSB:5gmk, PDBe:5gmk, PDBj:5gmk
PDBsum5gmk
PubMed27445308
UniProtP40968|PRP17_YEAST Pre-mRNA-processing factor 17 (Gene Name=CDC40)

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