Structure of PDB 8jdj Chain m Binding Site BS02

Receptor Information
>8jdj Chain m (length=121) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRK
SIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLNKHEENL
KTKKQQRKERLYPLRKYAVKA
Ligand information
>8jdj Chain F (length=156) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacuugcggccccggguuccucccggggcuacgccugucugagc
gucgcu
.........................................<<<<<<.<<
.....>>>.....(.<<<.(....>>.........)...>>>..)...>>
>....<<....>><<<<<<<<<.....>>>>>>>>>..............
......
Receptor-Ligand Complex Structure
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PDB8jdj Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		K5 S45 R48 R51 K52 A55 R56 L58 T59 N62 Q63 K66 R70 L81 R84 K86 T88 R89 R92
Binding residue
(residue number reindexed from 1)		K3 S43 R46 R49 K50 A53 R54 L56 T57 N60 Q61 K64 R68 L79 R82 K84 T86 R87 R90
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8jdj, PDBe:8jdj, PDBj:8jdj
PDBsum8jdj
PubMed37992713
UniProtP42766|RL35_HUMAN Large ribosomal subunit protein uL29 (Gene Name=RPL35)

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