Structure of PDB 6zu9 Chain m Binding Site BS02

Receptor Information
>6zu9 Chain m (length=147) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
INICRDNHDPFYRYKMPPIQAKVEGRGNGIKTAVLNVADISHALNRPAPY
IVKYFGFELGAQTSISVDKDRYLVNGVHEPAKLQDVLDGFINKFVLCGSC
KNPETEIIITKDNDLVRDCKACGKRTPMDLRHKLSSFILKNPPDSVS
Ligand information
>6zu9 Chain 1 (length=75) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcgccguggcgcaguggaagcgcgcagggcucauaacccugauguccuc
ggaucgaaaccgagcggcgcuacca
<<<<<<<..<<<<.......>>>>.<<<<<.......>>>>>.....<<<
<<.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
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PDB6zu9 A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Resolution6.2 Å
Binding residue
(original residue number in PDB)		G29 G31
Binding residue
(residue number reindexed from 1)		G27 G29
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003743 translation initiation factor activity
GO:0005092 GDP-dissociation inhibitor activity
GO:0005096 GTPase activator activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0008270 zinc ion binding
GO:0031369 translation initiation factor binding
GO:0071074 eukaryotic initiation factor eIF2 binding
Biological Process
GO:0001732 formation of cytoplasmic translation initiation complex
GO:0006412 translation
GO:0006413 translational initiation
GO:0006446 regulation of translational initiation
GO:0042256 cytosolic ribosome assembly
GO:0045947 negative regulation of translational initiation
Cellular Component
GO:0005829 cytosol
GO:0033290 eukaryotic 48S preinitiation complex
GO:0043614 multi-eIF complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zu9, PDBe:6zu9, PDBj:6zu9
PDBsum6zu9
PubMed33289941
UniProtP38431|IF5_YEAST Eukaryotic translation initiation factor 5 (Gene Name=TIF5)

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