Structure of PDB 8qfd Chain l Binding Site BS02

Receptor Information
>8qfd Chain l (length=50) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL
Ligand information
>8qfd Chain 8 (length=144) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagcu
agcugcgagaauuaaugugaauugcaggcgaucaucgacacuucgaacgc
acuugcggccccgggcccggggcuacgccugucugagcgucgcu
........................................<<<<<<<<<.
...>>>>.....<.<<<......>>.......>>>..>...>>>....<<
....>><<<<<<<<<>>>>>>>>>....................
Receptor-Ligand Complex Structure
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PDB8qfd The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons
Resolution2.2 Å
Binding residue
(original residue number in PDB)		T6 F7 K15 K18 Q19 R21 I23 P24 W26 M29 K30 T31 I35 K40
Binding residue
(residue number reindexed from 1)		T5 F6 K14 K17 Q18 R20 I22 P23 W25 M28 K29 T30 I34 K39
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0002227 innate immune response in mucosa
GO:0006412 translation
GO:0019731 antibacterial humoral response
GO:0050830 defense response to Gram-positive bacterium
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qfd, PDBe:8qfd, PDBj:8qfd
PDBsum8qfd
PubMed38383789
UniProtP62891|RL39_HUMAN Large ribosomal subunit protein eL39 (Gene Name=RPL39)

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