Structure of PDB 7pzy Chain l Binding Site BS02

Receptor Information
>7pzy Chain l (length=361) Species: 237561 (Candida albicans SC5314) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SRPQVSVISVKGEQGSSQLPLPAVFAAPVRPDLVHSVFVRVNKNKRQAYA
VAENAGHQTSAESWGTGRAVARIPRVGGGGTHRSGQAAFGNMCRGGRMFA
PTKTWRRWNVKVNHNEKRYATASAIAASAVTSLVLARGHRVEQVKELPLV
VSNEFESVTKTKDAVAVLKAVGAHKDVVKVIKSKKLRAGKGKLRGRRFTQ
RRGPLVVYAQDNGIVKALRNVPGVETASVKHLGLLQLAPGAHLGRFIIWT
QGAFESLDSVYGSDSTKSIKSGYTLPSNIISNTDVTRLINSAEVQAVVRP
AGEKTQKKSHVLKKNPLKNKQVLLRLNPYAKAYAAEKVGSAKVEQAKVKP
SKGQFAEVLKN
Ligand information
>7pzy Chain 4 (length=158) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaacuuucaacaacggaucucuugguucucgcaucgaugaagaacgcagc
gaaaugcgauacguaauaugaauugcagauauucgugaaucaucgaaucu
uugaacgcacauugcgcccucugguauuccggagggcaugccuguuugag
cgucguuu
.........................................<<<<<<.((
.....>>>.....<.<<<<.....))............>>.>>..>...>
>>....<<.....>><<<<<<<<<....>>>>>>>>>.............
........
Receptor-Ligand Complex Structure
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PDB7pzy E-site drug specificity of the human pathogen Candida albicans ribosome.
Resolution2.32 Å
Binding residue
(original residue number in PDB)		A50 A52 A54 K194 L195
Binding residue
(residue number reindexed from 1)		A48 A50 A52 K192 L193
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0009986 cell surface
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7pzy, PDBe:7pzy, PDBj:7pzy
PDBsum7pzy
PubMed35613268
UniProtA0A1D8PFV1|RL4B_CANAL Large ribosomal subunit protein uL4 (Gene Name=RPL4B)

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