Structure of PDB 7nwi Chain l Binding Site BS02

Receptor Information
>7nwi Chain l (length=50) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL
Ligand information
>7nwi Chain 8 (length=156) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacuugcggccccggguuccucccggggcuacgccugucugagc
gucgcu
.........................................<<<<<<.<<
.....>>>.....(.<<<......>>.............>>>..)...>>
>....<<<..>>><<<<<<<<.......>>>>>>>>..............
......
Receptor-Ligand Complex Structure
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PDB7nwi Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA.
Resolution3.13 Å
Binding residue
(original residue number in PDB)
R8 K15 R21 W26
Binding residue
(residue number reindexed from 1)
R7 K14 R20 W25
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7nwi, PDBe:7nwi, PDBj:7nwi
PDBsum7nwi
PubMed34157102
UniProtG1SYU7|RL39_RABIT Large ribosomal subunit protein eL39 (Gene Name=RPL39)

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