Structure of PDB 6gsm Chain l Binding Site BS02

Receptor Information
>6gsm Chain l (length=130) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VGLPYSELLSRFFNILRTPKFRIPPPVCLRDGKKTIFSNIQDIAEKLHRS
PEHLIQYLFAELGTSGSVDGKRLVIKGKFQSKQMENVLRRYILEYVTCKT
CKSINTELKRENRLFFMVCKSCGSTRSVSS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6gsm Chain l Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6gsm Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.
Resolution5.15 Å
Binding residue
(original residue number in PDB)		S261 C262
Binding residue
(residue number reindexed from 1)		S121 C122
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003743 translation initiation factor activity
Biological Process
GO:0006413 translational initiation

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Molecular Function
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Biological Process
External links
PDB RCSB:6gsm, PDBe:6gsm, PDBj:6gsm
PDBsum6gsm
PubMed34648019
UniProtP09064|IF2B_YEAST Eukaryotic translation initiation factor 2 subunit beta (Gene Name=SUI3)

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