Structure of PDB 8ip8 Chain ka Binding Site BS02

Receptor Information
>8ip8 Chain ka (length=193) Species: 4565 (Triticum aestivum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PGGDVKLFNRWTFEDVQVSDISLNDYLAVTSMKHYTFLPHSAGRYSAKRF
RKAQCPIIERLTNSLMMHGRNNGKKIMAVRIIKHTMEIIHLLTDANPIQI
IVDAIINSGPREDATRIGSAGVVRRQAVDISPLRRVNQAIYLLTTGARES
AFRNVKTIAECLADELINAAKGSSNSYAIKKKDEIERVAKANR
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8ip8 Chain ka Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8ip8 Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		A158 N161 K163
Binding residue
(residue number reindexed from 1)		A151 N154 K156
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ip8, PDBe:8ip8, PDBj:8ip8
PDBsum8ip8
PubMed38267667
UniProtW5D067

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