Structure of PDB 3jag Chain jj Binding Site BS02

Receptor Information
>3jag Chain jj (length=577) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISET
LCIGCGICIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPG
EVLGLVGTNGIGKSTALKILAGKQKPNLGKYDWQEILTYFRGSELQNYFT
KILEDDLKAIIKPQYVDQIPKAAKGTVGSILDRKDETKTQAIVCQQLDLT
HLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYLDVKQRLKAAI
TIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVTMPFSVRE
GINIFLDGYVPTENLRFRDASLVFMCMYKYPGMKKKMGEFELAIVAGEFT
DSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQKISPKS
TGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQRV
ALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEH
DFIMATYLADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDP
NNYRPRINKLNSIKDVEQKKSGNYFFL
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain3jag Chain jj Residue 600 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3jag Structural basis for stop codon recognition in eukaryotes.
Resolution3.65 Å
Binding residue
(original residue number in PDB)		C29 C38 I39 C55 I56 G57 C58 C61
Binding residue
(residue number reindexed from 1)		C26 C35 I36 C52 I53 G54 C55 C58
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0043024 ribosomal small subunit binding
Biological Process
GO:0000054 ribosomal subunit export from nucleus
GO:0006413 translational initiation
GO:0006415 translational termination

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3jag, PDBe:3jag, PDBj:3jag
PDBsum3jag
PubMed26245381
UniProtG1SG72

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