Structure of PDB 8s8j Chain j Binding Site BS02

Receptor Information
>8s8j Chain j (length=267) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSHCRFYENKYPEIDDIVMVNVQQIAEMGAYVKLLEYDNIEGMILLSELS
RRRIRSIQKLIRVGKNDVAVVLRVDKEKGYIDLSKRRVSSEDIIKCEEKY
QKSKTVHSILRYCAEKFQIPLEELYKTIAWPLSRKFGHAYEAFKLSIIDE
TVWEGIEPPSKDVLDELKNYISKRLTPAVKIRADVEVSCFSYEGIDAIKD
ALKSAEDMSTEQMQVKVKLVAAPLYVLTTQALDKQKGIEQLESAIEKITE
VITKYGGVCNITMPPKA
Ligand information
>8s8j Chain 1 (length=75) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcgccguggcgcaguggaagcgcgcagggcucauaacccugauguccuc
ggaucgaaaccgagcggcgcuacca
<<<<<<<..<<<<.......>>>>.<<<<<.......>>>>>.....<.<
<<.......>>>.>>>>>>>>....
Receptor-Ligand Complex Structure
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PDB8s8j Structural basis of AUC codon discrimination during translation initiation in yeast.
Resolution4.7 Å
Binding residue
(original residue number in PDB)
R57 S58 I59 Q60 K61 R64 S110 Y114 Y172 K175 R185 V223 A224 P226
Binding residue
(residue number reindexed from 1)
R55 S56 I57 Q58 K59 R62 S108 Y112 Y170 K173 R182 V220 A221 P223
External links
PDB RCSB:8s8j, PDBe:8s8j, PDBj:8s8j
PDBsum8s8j
PubMed39193907
UniProtP20459|IF2A_YEAST Eukaryotic translation initiation factor 2 subunit alpha (Gene Name=SUI2)

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