Structure of PDB 8rw1 Chain j Binding Site BS02

Receptor Information
>8rw1 Chain j (length=267) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSHCRFYENKYPEIDDIVMVNVQQIAEMGAYVKLLEYDNIEGMILLSELS
RRRIRSIQKLIRVGKNDVAVVLRVDKEKGYIDLSKRRVSSEDIIKCEEKY
QKSKTVHSILRYCAEKFQIPLEELYKTIAWPLSRKFGHAYEAFKLSIIDE
TVWEGIEPPSKDVLDELKNYISKRLTPAVKIRADVEVSCFSYEGIDAIKD
ALKSAEDMSTEQMQVKVKLVAAPLYVLTTQALDKQKGIEQLESAIEKITE
VITKYGGVCNITMPPKA
Ligand information
>8rw1 Chain 1 (length=75) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcgccguggcgcaguggaagcgcgcagggcucauaacccugauguccuc
ggaucgaaaccgagcggcgcuacca
<<<<<<<..<<<<.......>>>>.<<<<<.......>>>>>.....<<<
<<.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
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PDB8rw1 Structural basis of AUC codon discrimination during translation initiation in yeast.
Resolution3.35 Å
Binding residue
(original residue number in PDB)
R57 S58 K61 R64 K106 T107 S110 R113 Y114 E117 Y172 K175 R185 V223 A224
Binding residue
(residue number reindexed from 1)
R55 S56 K59 R62 K104 T105 S108 R111 Y112 E115 Y170 K173 R182 V220 A221
External links
PDB RCSB:8rw1, PDBe:8rw1, PDBj:8rw1
PDBsum8rw1
PubMed39193907
UniProtP20459|IF2A_YEAST Eukaryotic translation initiation factor 2 subunit alpha (Gene Name=SUI2)

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