Structure of PDB 8qfd Chain j Binding Site BS02
Receptor Information
>8qfd Chain j (length=86) Species:
9606
(Homo sapiens) [
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TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSA
KAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPK
Ligand information
>8qfd Chain 8 (length=144) [
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gacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagcu
agcugcgagaauuaaugugaauugcaggcgaucaucgacacuucgaacgc
acuugcggccccgggcccggggcuacgccugucugagcgucgcu
........................................<<<<<<<<<.
...>>>>.....<.<<<......>>.......>>>..>...>>>....<<
....>><<<<<<<<<>>>>>>>>>....................
Receptor-Ligand Complex Structure
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PDB
8qfd
The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
R20 R21 N57 T59 G60 G62 R63 M64 R65 H66 L67 R72 F74 H76 R79 E80 G81 T82 T83 P84 K85 P86 K87
Binding residue
(residue number reindexed from 1)
R19 R20 N56 T58 G59 G61 R62 M63 R64 H65 L66 R71 F73 H75 R78 E79 G80 T81 T82 P83 K84 P85 K86
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0003735
structural constituent of ribosome
GO:0019843
rRNA binding
GO:0046872
metal ion binding
Biological Process
GO:0006412
translation
Cellular Component
GO:0005737
cytoplasm
GO:0005840
ribosome
GO:0022625
cytosolic large ribosomal subunit
GO:1990904
ribonucleoprotein complex
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:8qfd
,
PDBe:8qfd
,
PDBj:8qfd
PDBsum
8qfd
PubMed
38383789
UniProt
A0A5J5MXE5
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