Structure of PDB 8p2f Chain j Binding Site BS02

Receptor Information
>8p2f Chain j (length=128) Species: 93061 (Staphylococcus aureus subsp. aureus NCTC 8325) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QVEYRGTGRRKNSVARVRLVPGEGNITVNNRDVREYLPFESLILDLNQPF
DVTETKGNYDVLVNVHGGGFTGQAQAIRHGIARALLEADPEYRGSLKRAG
LLTRDPRMKERKKPGLKAARRSPQFSKR
Ligand information
>8p2f Chain a (length=1526) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaaua
caugcaagucgagcgaacggacgagaagcuugcuucucugauguuagcgg
cggacgggugaguaacacguggauaaccuaccuauaagacugggauaacu
ucgggaaaccggagcuaauaccggauaauauuuugaaccgcaugguucaa
aagugaaagacggucuugcugucacuuauagauggauccgcgcugcauua
gcuaguugguaagguaacggcuuaccaaggcaacgaugcauagccgaccu
gagagggugaucggccacacuggaacugagacacgguccagacuccuacg
ggaggcagcaguagggaaucuuccgcaaugggcgaaagccugacggagca
acgccgcgugagugaugaaggucuucggaucguaaaacucuguuauuagg
gaagaacauauguguaaguaacugugcacaucuugacgguaccuaaucag
aaagccacggcuaacuacgugccagcagccgcgguaauacguagguggca
agcguuauccggaauuauugggcguaaagcgcgcguaggcgguuuuuuaa
gucugaugugaaagcccacggcucaaccguggagggucauuggaaacugg
aaaacuugagugcagaagaggaaaguggaauuccauguguagcggugaaa
ugcgcagagauauggaggaacaccaguggcgaaggcgacuuucuggucug
uaacugacgcugaugugcgaaagcguggggaucaaacaggauuagauacc
cugguaguccacgccguaaacgaugagugcuaaguguuagggggccccuu
agugcugcagcuaacgcauuaagcacuccgccuggggaguacgaccgcaa
gguugaaacucaaaggaauugacggggacccgcacaagcgguggagcaug
ugguuuaauucgaagcaacgcgaagaaccuuaccaaaucuugacauccuu
ugacaacucuagagauagagccuuccggacaaagugacagguggugcaug
guugucgucagcucgugucgugagauguuggguuaagucccgcaacgagc
gcaacccuuaagcuuaguugccaucauuaaguugggcacucuaaguugac
ugccggugacaaaccggaggaagguggggaugacgucaaaucaucaugcc
ccuuaugauuugggcuacacacgugcuacaauggacaauacaaagggcag
cgaaaccgcgaggucaagcaaaucccauaaaguuguucucaguucggauu
guagucugcaacucgacuacaugaagcuggaaucgcuaguaaucguagau
cagcaugcuacggugaauacguucccgggucuuguacacaccgcccguca
caccacgagaguuuguaacacccgaagccgguggaguaaccuuuuaggag
cuagccgucgaaggugggacaaaugauuggggugaagucguaacaaggua
gccguaucggaaggugcggcuggauc
.....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<<
<.<<<..<<<..<<.<<<<...<<<.........>.>>...>>>>.>>>>
>......<<........<<<<<<<..<<...<<<<<<<.<<<<.....<<
<<<<....>>>>>>......>>>>......<<<<<<<<<....>>>>>>>
>>......<<<<<<...>>>>>>.>>>>>>>..>>>>>>>>>.<<<....
<<<..<<<<<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<
....>>>>...>>>>.>>.<<<<<.<.........>>>>>>.<<<<....
>>>>...>>>>>>>........<<<....<<<<....>>>>..>>>..>>
.>>>>>>..<<<<......<<<<....>>>>.....>>>>...<<<<<<<
.......<.<<<<<<<........>>>>>>>.>........>>>>>>...
>..<<<<<(((...<<<<<.....<<.)))>>.......>>>>>>>>>>.
.>>>>>>>>>..........<<<((.....<<<<<..<<<.<<<<<<<.<
<<<<<<<<.......<<<<<<.....>>>>>>.....>>>>>>>..>>>>
>>>>>...<<<<<<<<...<<<<<<<....<<<<<<<<...<<<......
>>>......>>>>>>>>...........<<....>>.>>>>>>>..>>>>
>.>>>...>>>..>>>>>....<<<<<<<...<...<<<<.........>
>>>...>>>>>>>>..........<<<<<<..<<<<<<<<<<<..>>>>>
>>>>>>...<<..))>>.....>>>>>>.>>>.<<<......<<<<....
>>>>....>>>..)))).]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<
<<<<......<<........>>..........<<<<<<<......<<<<<
<<....<<<<<....>>>>>.........>>>>>.>>.<<<.<<<..<<<
<<<.......<<<<<<<<<....>>>..<<<<......>>>>..>>>>>>
.....<<<<.<<<<<<<..<<<..<<......>>>>>...>>>>>>>...
..<<<<<.....>>>>>........>>>>.........>>>...>>>>>>
>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<
<...<<<....>>>...>>....>>>.....>>>>>>>......<....<
<<<<<<........>>>>>>>....>.....>>>>>>....<<<<<<<..
.......>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<.
<<<<.<<<..<<<<<<..<<<<....<.<<<<..<<<..<<<...>>>.>
>>.>>>>.>...>>>>..>>>>>>..>>>.>>>>..>.>>...>.....<
<<<<<<<<....>>>>>>>>>.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8p2f Cryo-EM structures of Staphylococcus aureus 70S ribosomes in complex with elongation factor G and fusidic acid
Resolution2.44 Å
Binding residue
(original residue number in PDB)
R9 T11 R13 R14 K15 N16 R20 R22 R35 Y40 H70 G71 G72 G73 F74 T75 Q77 R87 R97 K101 T107 R108 R111 M112 K113 R115 K116 K117 P118 G119 K121 R124 R125 S126 Q128 F129 K131 R132
Binding residue
(residue number reindexed from 1)
R5 T7 R9 R10 K11 N12 R16 R18 R31 Y36 H66 G67 G68 G69 F70 T71 Q73 R83 R93 K97 T103 R104 R107 M108 K109 R111 K112 K113 P114 G115 K117 R120 R121 S122 Q124 F125 K127 R128
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8p2f, PDBe:8p2f, PDBj:8p2f
PDBsum8p2f
PubMed38902339
UniProtQ2FW39|RS9_STAA8 Small ribosomal subunit protein uS9 (Gene Name=rpsI)

[Back to BioLiP]